Fluoxetine: profile and news






Paul Taylor's NY Premieres Evoke Spring, Death: Tobi Tobias  Mar 1, 2006
By Tobi Tobias. March 1 (Bloomberg) -- In filmy costumes tinted the pale green of budding leaves, a boy and girl enjoy an innocent caress. ... - Bloomberg

Tobi Kahn exhibit  Feb 19, 2006
Impact: Programs of Excellence had an opening reception with artist Tobi Kahn on Feb. 7 at the Adair Margo Gallery, 415 E. Yandell. ... - El Paso Times,

Constance White, eBay Style Director  Mar 3, 2006
A fabulous Hollywood wind blew into the suite with designer Randolph Duke, who brought his buddies interior designer Tobi Tobin and publicist Richard Pollman. ... - Splendora,

Tobi inaugurates tourism workshop - Oman  Jan 31, 2006
MUSCAT — Mohammed bin Hamoud Al Tobi, undersecretary at the Ministry of Tourism inaugurated a workshop on tourism investment avenues in the Sultanate ... - Middle East North Africa Financial Network,

March With Mark: Morris Celebrates 25 Years of Dancing at BAM  Mar 5, 2006
By Tobi Tobias. March 5 (Bloomberg) -- Celebrating the 25th anniversary of his company with a three-week season at the Brooklyn Academy ... - Bloomberg

Al Rumaihi steals the limelight  Mar 5, 2006
Junior 2/3 (10 riders): 1 Ali Mirza/Geno (109.06), 2 Salman Isa/Popeye (110.10), 3 Emily Atkinson/Tobi, 4 Ali Mirza/Kaleidoscope. ... - Gulf Daily News,

For lesbian, transgender son brings pride and worry  Feb 26, 2006
Two years later, Toby now considers herself a "transwoman." She's on a regimen of female hormones and has legally changed her name from Tobias to Tobi. ... - The Register-Guard,

Brown Denies Rift With Brough  Feb 28, 2006
In Brough's absence, Brown has now laid down the gauntlet to transfer-listed Tobi Jinadu to cement a regular starting place after an encouraging performance on ... - Scottish Fitba,

(Afkomstig van dj/agency)  Feb 23, 2006
Multitalent Tobi Neumann lives in Berlin. He ... Tobi Neumann is now in the artist roster of Sven Väth's DJ-booking agency Cocoon. His ... - Go magazine,

Top of the Week | Religious events calendar  Mar 4, 2006
AVODA-Objects of the Spirit: Art exhibit opens displaying 42 ceremonial Jewish objects and pieces of art by painter and sculptor Tobi Kahn; reception 6 pm ... - Miami Herald,

MIAMI-DADE ART FAIRS AND GALLERY WALKS  Mar 3, 2006
AVODA: Objects of the Spirit, 42 pieces of Jewish ceremonial art by painter and sculptor Tobi Kahn: 6 pm March 6, continues through Aug. 20. ... - Miami Herald,

Alpha Phi Omega revived at Clarion University  Mar 3, 2006
Kristen Park, a senior elementary education major, a daughter of Christopher and Tobi Park of North Wales, and a graduate of North Penn High School. ... - Clarion University News,

Now the real fun starts.  Mar 3, 2006
What will be the best final? Detwiler-Fiorito, probably, but a fresher matchup could pit Boyertown's Josh White against Tobi Showunmi of Pennsbury at 215. ... - phillyBurbs.com,

AAA and AA wrestling tournament results  Mar 3, 2006
S-1 Jr. Kris Wazlawik, Garnet Valley (33-2); N-2 Sr. Tobi Showumni, Pennsbury (41-2) vs. S-3 Sr. Bill Kent, Upper Darby (27-7), winner vs. 12-1 Sr. ... - phillyBurbs.com,

NP's Hill rolls past top seed  Mar 4, 2006
Nojan Zommorrodian, DW, 9-2; Josh White, Bo, pinned Kenton Remmey, CBW, 5:05; Kris Wazlawik, GaV, dec. Gregg Nestel, Con, 7-6; Tobi Showunmi, Penns, maj. dec. ... - phillyBurbs.com,

The 5-Minute Neighbors  Mar 5, 2006
...• AVODA-Objects of the Spirit: Features 42 pieces of Jewish ceremonial art by painter and sculptor Tobi Kahn and opens Monday with a reception at 6 pm The ... - Miami Herald,

Quiksilver and Rossignol Congratulate Their Sponsored Athletes for ...  Mar 3, 2006
The Bronze medalist athletes included: Bruno Kernen of Switzerland, Men's Downhill (Rossignol); Tobi Dawson of the USA, Men's Moguls (Rossignol); Sandra Laoura ... - Business Wire (press release),

11 area wrestlers reach semis  Mar 4, 2006
..."I feel pretty good, but I won't feel good until I'm definitely in states," he said. Pennsbury's semifinalists are Tobi Showunmi (215) and Jack Lee (275). ... - phillyBurbs.com,

Diller Overhauls Ask.com  Feb 28, 2006
...by Tobi Elkin, Tuesday, Feb 28, 2006 6:00 AM EST. KICKING OFF THE COMING OUT party for the revamped Ask.com search engine, IAC Chairman ... - Mediapost.com,

Optometrists counsel Nigerians on eye health  Feb 27, 2006
...of topics will also be presented at the professional conference earmarked for the Sheraton Hotel on March 10, under the chairmanship of Otunba Tobi Fele, MD ... - Vanguard,

Pennsbury's Lee trying to make up for lost time  Mar 1, 2006
Lee likes practicing with teammates Bill Farrell, a 189-pounder with good technical skills, and Tobi Showunmi, a 215-pounder with exceptional speed. ... - phillyBurbs.com,

College notes  Feb 28, 2006
Christina Policastro, Evelyn Potter, Lacey Ragule, Amanda Reardon, Maya Rook, Yelena Rudyak, Kristina Santos, John Sardo, Steven Scherr, Tobi Schnier, Kerry ... - Poughkeepsie Journal,

Baker, Lee selected to All-CAC teams  Feb 28, 2006
Singles: Garcia de Andoain (L) d. Bristow 6-4, 2-6, 6-4; Patnikov (L) d. James 6-3, 5-7, 7-5; Clair (UMW) d. Tobi Guennel 6-0, 6-4; Lindsley (L) d. Loden 6-3, 6 ... - The Free Lance-Star,

Word of mouth can grow business  Feb 24, 2006
By TOBI BRUHN. Commerce corner ... county. Tobi Bruhn is interim executive director of the Bucks County Community College Foundation. For ... - phillyBurbs.com,

Here's who's going to Hershey  Mar 1, 2006
CR South. Josh White, Boyertown; Tobi Showunmi, Pennsbury; Derek Bennett, Upper Perkiomen; Kris Wazlawik, Garnet Valley. Jack Lee ... - phillyBurbs.com,

Vocalists to entertain at ISAAC banquet  Mar 2, 2006
Both Vivian and the Mosaic group fit with part of ISAAC's overall vision, according to ISAAC vice president for communication Tobi Hanna-Davies. ... - MLive.com,

Pets: They get what they want. Do you?  Mar 2, 2006
..."Communication in the business world is essential, but it's a very theoretical topic," said Tobi Bruhn, the foundation's executive director. ... - phillyBurbs.com,

The Seamy Underside Of Reality  Feb 24, 2006
...by Tobi Elkin, Friday, Feb 24, 2006 8:15 AM EST. ... Tobi Elkin is Executive Editor, MediaPost. Contact her at telkin@mediapost.com. - Mediapost.com,

Kumeiti enters Grand Prix fray  Feb 23, 2006
BD250. Rising rider Natasha Owen (34.69) finished second on Duell Time and Emily Atkinson (36.34) was third on Tobi. Abdulrahman ... - Gulf Daily News,

Hawks just can't stay in the lead  Mar 2, 2006
...for the Hawks. Tobi Ositola was unavailable due to illness but Leon Lalite was back in the starting line-up. Beckett Hollenbach ... - Herts 24,

Britt and McGrath Top List of NCTA's 2006 Vanguard Honorees  Mar 2, 2006
For more information, contact Tobi Brown in NCTA Industry Affairs at 202/775-3669. The event is open to the media at no cost, but reservations are mandatory. ... - Yahoo! News (press release)

EDGUY Frontman: Corrupt Police Officers Disturb Band's Beauty ...  Feb 9, 2006
...world were long gone. Half asleep I replied, 'It's not Manni, it's Tobi!' Then one of the sheriffs asked me for drugs. I mean, even ... - Blabbermouth.net,

Novartis: Strengthening Its Infectious Disease Portfolio  Feb 9, 2006
The acquisition of Chiron will add to this, providing Novartis with two key anti-infectives - Tobi (tobramycin), an inhalable antibacterial used for infections ... - International News Service,

Shots List Trio  Feb 16, 2006
...press release by the club, Nick Fryer has announced that three Shots players have been made available for loan or transfer, both centre half - Tobi Jinadu and ... - Scottish Fitba,

Peter Martins's `Friandises' at NYCB Has Thrills, Little Depth  Feb 13, 2006
By Tobi Tobias. Feb. ... 26. For tickets, call (1) (212) 721-6500. To contact the writer of this review: Tobi Tobias in New York at wildcat_enterprises@yahoo.com. - Bloomberg

Oman Travel Market in progress  Feb 2, 2006
Rashaad Bin Ahmed Al Hanai, in the presence various senior government officials and dignitaries such as Mohammed bin Hamoud Al Tobi, undersecretary at the ... - TravelVideo.tv (press release)

Wednesday 22nd, February, 2006  Feb 21, 2006
Although at its inauguration he said the conference would have no go areas, the Chairman of the conference, Justice Niki Tobi, allowed discussion on certain ... - Nigeria Daily Independent,

Tel Browned Off With His Yorkshire Puddings  Feb 14, 2006
Half-time saw the boss look to tighten things up at the back, replacing an apparently injured Brough with Elphick, who got the nod over Tobi Jinadu despite his ... - Scottish Fitba,

IDM and GENESIS Pharma Sign an Exclusive Marketing Agreement for ...  Feb 21, 2006
Some products introduced by GENESIS Pharma include Aranesp, Avonex, Granulokine, Kineret, Modiodal, Neulasta, Tobi and Venofer. ... - International News Service,

Police look to keep trails safe  Feb 20, 2006
By TOBI COHEN, OTTAWA SUN. Sailing along a hilly wooded trail, the wind whipping off the side of your helmet as a deer crosses your ... - Ottawa Sun,

Comeback Not Enough For Shots  Feb 23, 2006
John Brough's sorry night ended by being replaced by transfer-listed Tobi Jinadu five minutes into the re-start, citing an old hip injury as the cause. ... - Scottish Fitba,

‘Big Meet’ a splashing success  Feb 22, 2006
Other Stanford highlights included Sun taking first in the 200 back, senior Tobi Oriwol winning the 200 IM and sophomore Nathan Kim claiming the top finish in ... - Stanford Daily,

Injury Mess Ahead Of Bulls Clash  Feb 21, 2006
Transfer-listed trio Tarkan Mustafa, Tobi Jinadu and Hassan Sulaiman are all up for selection as Brown will have to do some serious re-shuffling to put out a ... - Scottish Fitba,

CR-South advances 9 to semifinal round  Feb 25, 2006
Pennsbury is in seventh place with four semifinalists: Chris Maples (135), Bill Farrell (189), Tobi Showunmi (215) and Jack Lee (275). - phillyBurbs.com,

Snowmobile safety pleas fall on deaf ears  Feb 22, 2006
By JON WILLING AND TOBI COHEN, OTTAWA SUN. Police and recreation clubs are wondering what more they can do to keep snowmobilers off thin ice. ... - Ottawa Sun,

Stolen car slams snowplow while fleeing cops  Feb 22, 2006
By TOBI COHEN, OTTAWA SUN. A high-speed police chase involving a stolen car has landed two Ottawa teens in hospital after they slammed ... - Ottawa Sun,


Other information


Indication
For the treatment of depression; Obsessive compulsive disorder; Bulimia nervosa

Pharmacology
Fluoxetine, an antidepressant agent belonging to the selective serotonin reuptake inhibitors (SSRIs), is used to treat depression, bulimia nervosa, premenstrual dysphoric disorder, panic disorder and post-traumatic stress. According to the amines hypothesis, a functional decrease in the activity of amines, such as serotonin and norepinephrine, would result in depression; a functional increase of the activity of these amines would result in mood elevation. Fluoxetine's effects are thought to be associated with the inhibition of 5HT receptor, which leads to an increase of serotonin level.

Mechanism Of Action
Metabolized to norfluoxetine, fluoxetine is a selective serotonin-reuptake inhibitor (SSRI), it blocks the reuptake of serotonin at the serotonin reuptake pump of the neuronal membrane, enhancing the actions of serotonin on 5HT1A autoreceptors. SSRIs bind with significantly less affinity to histamine, acetylcholine, and norepinephrine receptors than tricyclic antidepressant drugs.

Drug Category
Antidepressants, Second-Generation; Selective Serotonin Reuptake Inhibitors (SSRIs); ATC:N06AB03

Brand Names/Synonyms
Animex-On; Deprex; Eufor; Fluctin; Fluoxeren; Fluoxetina [Inn-Spanish]; Fluoxetina [Spanish]; Fluoxetine; Fluoxetine Hcl; Fluoxetine Hydrochloride; Fluoxetine Hydrochloride: Adofen; Fluoxetinum [Inn-Latin]; Fluval; Fontex; Foxetin; HSDB 6633; Portal; Prozac; Prozac Weekly; Pulvules; Reneuron; Sarafem

Dosage Forms
CAPSULE; LIQUID; SOLUTION

Absorption
72%

Interactions
Do not take this medicine with thioridizine, or within 5 weeks of taking fluoxetine. Talk to your doctor if you are taking certain antibiotics such as erythromycin, clarithromycin or azithromycin. This medicine should not be taken with MAO inhibitors. Caution should be exercised when taking this medicine certain antibiotics, such as erythromycin, clarithromycin, or azithromycin. This medicine should not be taken with MAO inhibitors. If you think you are taking an MAO inhibitor talk to your doctor or pharmacist. Do not take this medicine with St. John's Wort because of the additive effects of sertonin. This medication should not be taken with MAO inhibitors. Your doctor or pharmacist can give you more information on MAO inhibitors. Wait 5 weeks after stopping escitalopram before starting a non-selective MAO inhibitor. Wait 2 weeks after stopping an MAO inhibitor before starting escitalopram. If you are taking medications for migraines such as Imitrex, talk to your doctor before starting this medicine. If you are taking a tricyclic antidepressant, talk to your doctor before taking this medicine. St. John¡¯s Wort should be avoided while taking this medicine due to the additive effects of serotonin. Tell your doctor if you are taking any of the following drugs: blood thinners (Coumadin) other antidepressants metoprolol antihistamines carbamazepine (Tegretol) cimetidine (Tagamet) estrogens fluoxetine (Prozac) intraconazole (Sporanox) ketoconazole (Nizoral) levodopa lithium muscle relaxants birth control pills sleeping pills thyroid medications

Chemical IUPAC Name
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-propan-1-amine

Chemical Formula
C17H18F3NO

Half Life
1 to 3 days

Drug Type
Approved Drug

# Accession No
APRD00530

CAS Registry Number
54910-89-3

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