Errin: profile and news






Sports Nutrition  07 Mar 2006
62 One B vitamin with a specialized role in athletes is niacin (B3), which is involved in carbohydrate metabolism. Australian researchers ... - Natural Products Industry Insider,

Maintain a Healthy Heart with Clinicians Choice  07 Mar 2006
Fortified with Folic Acid, Niacin, B6, B12, Beta Sitosterol, Vitamin C, Selenium, and CoEnzyme Q10, Cardio Guardian naturally controls homocysteine and ... - PR Leap (press release),

SoBe Introduces 'SoBe Life Water'  07 Mar 2006
Water provides 20% of the recommended daily value of Vitamin E, as well as 10% of the recommended daily value of the B Vitamins B6 and B12, Niacin (B3) and ... - PR Newswire (press release),

Merck: Out Of The Ivory Tower  Feb 28, 2006
15 analyst meeting. The plan was, in essence, to tweak niacin, a well-known vitamin that raises "good" cholesterol, and turn it into a blockbuster. ... - BusinessWeek

Busting the myth  Mar 5, 2006
...that dairy will trigger asthma or produce mucus, may inadvertently deprive their children of important nutrients such as protein, calcium, riboflavin and niacin ... - Euroa Gazette,

Kos Reports Summary Results of Key Phase IV Research and ...  Feb 23, 2006
This study was a single dose, double-blind, randomized,placebo-controlled three-way crossover, human study (N=156) evaluatinga Niaspan (niacin extended-release ... - Finanzen.net,

Natural Ways To Lower Cholesterol  Feb 27, 2006
Niacin in high doses has shown benefits for reducing cholesterol. However, if taking other medications, consult a physician as niacin ... - DailyIndia.com,

Singing praises of peanut butter  Mar 4, 2006
It's a vegetarian source of protein, it's a great source of niacin and phosphorous, and it's a terrific source of folic acid, which is an essential nutrient ... - Press-Enterprise (subscription),

The Healthy Beef Cookbook  Feb 28, 2006
9 g fat (2 g saturated fat; 4 g monounsaturated fat); 61mg cholesterol; 531 mg sodium; 66 g carbohydrate; 6.2 g fiber; 36 g protein; 8.4 mg niacin; 0.8 mg ... - commercialappeal.com (subscription),

Good Skin Care begins with nourishment from the inside out  Feb 26, 2006
B-complex: The B vitamins as a whole, B1 (Thiamine), B2 (Riboflavin), B3 (Niacin), B5 (Pantothenic acid), B6 (Pyridoxine) and B12 (Cyancobalamine), help ... - DailyIndia.com,

Eat your wheat  Feb 22, 2006
2-ounce serving has 7 grams of fiber and 8 grams of protein and is a good source of iron and riboflavin and an excellent source of thiamin, niacin and folic ... - Rockford Register Star,

Do you tofu?  Mar 1, 2006
...sodium. It contains no cholesterol, but comes equipped with vitamins A and C, thiamin, riboflavin, calcium, iron and niacin. Because ... - The Grand Rapids Press,

Collierville High Student Arrested for bringing Drugs to School  Feb 23, 2006
...a friend. She also told police the capsule in question was a 'niacin' pill. Niacin is typically used to lower cholesterol. "Our ... - WREG,

The Truth about C Reactive Protein and Cholesterol Lowering Drugs  Feb 26, 2006
Niacin--Niacin is a B-complex vitamin that works so well to lower cholesterol and C-reactive protein that it is regulated by the FDA and available by doctors ... - DailyIndia.com,

Using maple syrup for beef dishes  Mar 1, 2006
7 g fat (2 g saturated fat; 4 g monounsaturated fat); 60 mg cholesterol; 511 mg sodium; 42 g carbohydrate; 5.3 g fiber; 26 g protein; 5.2 mg niacin; 0.7 mg ... - Mount Vernon News,

Connie Aclin: Crawfish can be saved for later - if you can afford ...  Mar 3, 2006
...value. Crawfish are an excellent source of protein, calcium, phosphorous, iron and the B vitamins (thiamine, riboflavin and niacin). ... - Shreveport Times,

Créme Brulee  Mar 2, 2006
...products such as milk, cheese and yogurt provide nine essential nutrients including calcium, potassium, protein, phosphorus, riboflavin, niacin and Vitamins A ... - 9NEWS.com,

Peanuts find their way into cookies, candy, other desserts  Mar 1, 2006
...cancer; they are a good source of protein, vitamin E and fiber; and contain other vitamins and minerals such as folic acid, thiamin, niacin, copper, manganese ... - MyWestTexas.com,

White: Sweeten things up with honey  Mar 1, 2006
...primarily of carbohydrates and water, but it also contains small amounts of a wide array of vitamins and minerals, including niacin, riboflavin, pantothenic ... - Broomfield Enterprise (subscription),

Cleaning and storage  Feb 28, 2006
Do not clean them until ready to use. Mushrooms are a good source of potassium, silenium and the B-complex vitamins niacin and riboflavin. - Winston-Salem Journal,

Go, See, Do  Mar 1, 2006
Old Union with Delta Moon, 10 pm, 3rd & Lindsley, 818 Third Ave. S. 259-9891. $8. Totemsoul with Niacin Flush, 8 pm, The 5 Spot, 1006 Forrest St. 650-9333. $5. ... - Nashville City Paper,

The Lowdown on High Triglycerides  Feb 14, 2006
Niacin (sometimes called nicotinic acid), one of the B vitamins, is a "threefer:" It cuts LDL cholesterol a little, increases HDL ("good") cholesterol a lot ... - Gilroy Dispatch (subscription),

Lowdown on what having high triglycerides means  Feb 13, 2006
Niacin, one of the B vitamins, is a "threefer": It cuts LDL cholesterol a little, increases HDL ("good") cholesterol a lot, and also lowers triglycerides. ... - Charleston Post Courier (subscription),

And, take its health seriously  Feb 15, 2006
And let’s not forget the vitamins. Niacin is aB vitamin and the first vitamin to be recognized as having cholesterol lowering properties. ... - Knoxville Metro Pulse,

Arena Pharmaceuticals Announces Fourth Quarter and Full Year 2005 ...  Feb 22, 2006
...three GPCRs with the potential to regulate plasma lipid profiles, including HDL, or the "good" cholesterol, similar to the therapeutic action of niacin. ... - MSN Money

Cardiovascular disease: fruitful findings?  Feb 23, 2006
...raising drugs. Currently, niacin is the only potent HDL raiser on the market, but the drug is plagued with adverse side effects. In ... - Drinks Business Review

ASK THE DOCTOR: Diet, exercise and other habit changes can help ...  Feb 6, 2006
Medications: There are several classes of medications that can raise your HDL cholesterol. The two most often used are niacin and fibrates. ... - Asheville Citizen-Times,

Carnegie Library served black residents  Feb 23, 2006
Dr. Henry Green, an internationally renowned authority on pellagra, a vitamin deficiency disease caused by a lack of niacin, and a former president of the ... - Knoxville News Sentinel (subscription),

The Orphan Child of Soy  Feb 22, 2006
It is a good source of the B-Vitamins riboflavin, niacin and vitamin B-6. Finally, tempeh supplies minerals like iron, magnesium, phosphorus and zinc and is ... - The Green Guide,

What's really in them?  Feb 24, 2006
Potatoes, Partially Hydrogenated Soybean Oil, enriched bleached flour (wheat flour, niacin, iron, thiamine mononitrate, riboflavin, folic acid), salt, modified ... - Pittsburgh Tribune-Review,

Join Mary in having a little lamb  Feb 26, 2006
You’ll get 55 percent of your vitamin B-12, 42 percent of your niacin, 30 percent of your zinc, 17 percent of your riboflavin, 12 percent of your iron, 10 ... - Fort Wayne Journal Gazette,

Spuds take the spotlight  Feb 7, 2006
Like other vegetables, Beatty says, potatoes not only contain a wealth of nutrients, such as potassium, vitamins C, B6, B1, folic acid and niacin, but a wide ... - London Free Press,

Feeding The Geriatric Horse  Feb 19, 2006
Because the liver also is a site of the synthesis of B vitamins (especially niacin) and vitamin C, affected horses should be fed a diet supplemented with oral ... - TheHorse.com,

Nutritional supplements key in treating people with heart disease  Feb 5, 2006
L-Arginine is an amino acid that can be formed by the body with made by the body with adequate amounts of L-glutamate, L-glutamine, niacin, and vitamin B-6. L ... - Health Sentinel

COLUMN: Eggs offer versatility and good nutrition  Feb 19, 2006
A large egg contains 70 calories, lots of high quality protein, Vitamins A, B6, B12, D, E thiamine, riboflavin, niacin, folate and other significant minerals. ... - Coquitlam Tri City News,

Essential nutrients for pregnancy  Feb 20, 2006
...have unbalanced eating habits, you need to take a supplement that contains vitamin C and the B-complex vitamins (thiamin or B1, riboflavin or B2, niacin or B5 ... - Health24.com,

Getting A Healthy Breakfast  Feb 21, 2006
Fresh eggs are good breakfast food because they are rich in complete protein, fat, iron, calcium, phosphorus, vitamins A & B, and niacin. ... - DailyIndia.com,

Key Ingredient: Zucchini scores high in nutrition, versatility  Feb 22, 2006
...gives the vegetable kudos for being low in calories (about 20, for 1 cup chopped with the peel), high in dietary fiber, iron, manganese, niacin, potassium and ... - Cherry Hill Courier Post,

Crazy for Brazil nuts  Feb 21, 2006
Nutrient-dense, Brazil nuts are 17 percent protein and contain folic acid, magnesium, phosphorous, thiamin, niacin, vitamin B6, calcium, iron, potassium, zinc ... - Newark Star Ledger,

Legumes: Good for People and Soil  Feb 20, 2006
As a food, beans are high in protein. Most beans also contain a lot of nutrients such as calcium, iron, phosphorus and niacin. Some ... - Voice of America

166 grams of tempeh a day keeps doctors away  Feb 4, 2006
Tempeh also contains micro amounts of other nutrients which are needed by the body such as calcium, iron, potassium, zinc and niacin. ... - Jakarta Post,

The Fat Hits the Fire at Kos  Feb 6, 2006
Niaspan is a controlled-release version of Niacin-vitamin B3-that can raise the level of HDL cholesterol in the blood by between 15% and 30%. ... - Business New Jersey (subscription),

Platkin column: Nutrition definitions  Feb 21, 2006
With flour, thiamin, riboflavin, iron and niacin lost in the translation from wheat to white are often added again to the final white flour. - The State,

Dark-meat chicken a tasty alternative  Feb 22, 2006
You'll get 40 percent of your selenium, 34 percent of your niacin, 18 percent of zinc, 16 percent of B-6, 13 percent of riboflavin, 8 percent of iron, 7 ... - Charleston Post Courier (subscription),


Other information


Indication
For use as an oral contraceptive in the prevention of pregnancy.

Pharmacology
Norethindrone is a synthetic oral progestin. It is used for contraception or to treat such conditions as secondary amenorrhea, abnormal uterine bleeding, and endometriosis. As an oral contraceptive, norethindrone is available as either a single agent or in combination with an estrogen.

Mechanism Of Action
Progestins diffuse freely into target cells and bind to the progesterone receptor. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once bound to the receptor, progestins slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH surge.

Drug Category
Contraceptives, Oral, Synthetic; Progestins; ATC:G03CA

Brand Names/Synonyms
Anhydrohydroxynorprogesterone; Anovulatorio; Anovule; Aygestin; Binovum; Brevicon; Brevinor; Brevinor 21; Brevinor 28; Brevinor-1 21; Brevinor-1 28; CCRIS 484; Camila; Ciclovulan; Conceplan; Conludaf; Conludag; Demulen; ENT; Errin; Estrinor; Ethinylnortestosterone; Ethynylmortestosterone; Ethynylnortestosterone; Gencept; Genora; Gestest; HSDB 3370; Jenest; Jenest-28; Levlen; Loestrin; Menzol; Microneth; Micronett; Micronor; Micronovum; Milli; Mini-Pe; Mini-Pill; Minovlar; Modicon; N.E.E.; NET; NSC-9564; Necon; Nelova; Neocon; Nodiol; Nor-Q.D.; Nor-Qd; Noraethisteronum; Noralutin; Norcept; Norcept-E; Norcolut; Nordette; Noresthisterone; Norethadrone; Norethin; Norethin 1/35 E; Norethin 1/50 M; Norethindrone; Norethindrone Acetate; Norethindrone Norethisterone; Norethisteron; Norethisterone; Norethisterone [Progestins]; Norethisteronum [Inn-Latin]; Norethyndron; Norethynodron; Norethynodrone; Noretisterona [Inn-Spanish]; Noretisterone [Dcit]; Norfor; Norgestin; Noriday; Noriday 28; Norimin; Norinyl; Norlestrin; Norlutate; Norluten; Norlutin; Norluton; Normapause; Norpregneninlone; Norpregneninolone; Norpregneninotone; Orlest; Ortho 1 35; Ortho 7 7 7; Ortho-Novum; Ortho-Novum 1 35; Ortho-Novum 1 50; Ortho-Novum 7 7 7; Ovcon; Ovral; Ovrette; Ovysmen; Ovysmen 0.5 35; Ovysmen 1 35; Palonyl; Perovex; Primolut N; Primolut-N; Proluteasi; SC 4640; Synphase; Synphasic 28; Tri-Levlen; Tri-Norinyl; Triella; Trinovum; Trinovum 21; Utovlan; Utovlar

Dosage Forms
TABLET

Absorption
Absolute oral bioavailability approximately 64%

Interactions
Interactions for Norethindrone:

The effectiveness of progestin-only pills is reduced by hepatic enzyme-inducing drugs such as the anticonvulsants phenytoin, carbamazepine, and barbiturates, and the antituberculosis drug rifampin. No significant interaction has been found with broad-spectrum antibiotics.



Chemical IUPAC Name
17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one

Chemical Formula
C20H26O2

Half Life
7 hours

Drug Type
Approved Drug

# Accession No
APRD00679

CAS Registry Number
68-22-4

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