Elavil: profile and news

Ex-ghostbuster seeks to become chart-buster  Mar 5, 2006
...of his dream drug cabinet: "I’m on Ritalin, Coumadin, Zantac, Lipitor / Diazepam, Nexium, Prevacid, Percocet / Levitra, Levaquin, Elavil, Fosamax / Plavix ... - Columbus Dispatch,

Antidepressants and your libido  Feb 28, 2006
The answer may lie in switching to one of the older antidepressant tricyclate drugs such as Elavil or Imipramine, or one of the MAO Inhibitors like Parnate or ... - Health24.com,

ANIMAL DOCTOR Are nuts good as bird feed?  Feb 3, 2006
Your veterinarian can prescribe psychotropic medications, such as Prozac and Elavil, that may greatly improve your dog's emotional stability, quality of life ... - Houston Chronicle,

Study Finds Cymbalta® Was As Safe And Well-Tolerated As Routine ...  Feb 20, 2006
The most commonly used prescription pain medications for routine care included Neurontin® (gabapentin), Elavil® (amitriptyline) and Effexor-XR® (venlafaxine ... - Medical News Today (press release),

Ky. cabbie was high, police say  Feb 9, 2006
Dean told a police officer he was taking antidepressants Prozac and Elavil in addition to cocaine, according to the police report. ... - Cincinnati.com,

Consumer Reports Medical Guide Addresses Differing Side Effects of ...  Feb 10, 2006
...men consult with their doctor about increasing starting dosages or perhaps switching to older tricyclic anti-depressants (Aventyl, Elavil, Pamelor, Torfranil ... - U.S. Newswire (press release),

Study: Antidepressants pose risks for newborns  09 Feb 2006
These include tricyclics such as amitriptyline sold as Elavil, bupropion sold as Wellbutrin, venlafaxine sold as Effexor and trazodone sold as Desyrel. ... - San Diego Union Tribune,

Ky. cabbie was high, police say  09 Feb 2006
Dean told a police officer he was taking antidepressants Prozac and Elavil in addition to cocaine, according to the police report. ... - Cincinnati.com,

ANIMAL DOCTOR Are nuts good as bird feed?  Feb 3, 2006
Your veterinarian can prescribe psychotropic medications, such as Prozac and Elavil, that may greatly improve your dog's emotional stability, quality of life ... - Houston Chronicle,

Ask Dr. H | Old-timey ailments with quaint names  Jan 16, 2006
...or tincture. Before Elavil and Prozac, the herbs skullcap and mugwort were often combined to aid in treating depression. St. Vitus ... - Philadelphia Inquirer,

Old disease names altered over time Ask Dr. H Mitchell Hecht  Jan 17, 2006
...tincture. Before Elavil and Prozac, the herbs skullcap and mugwort were often combined to aid in the treatment of depression. St. ... - Wilkes Barre Times-Leader,

Exact cause of restless legs is unknown  Jan 9, 2006
Also, certain medications, such as the tricyclic antidepressants (ie Elavil), selective serotonin reuptake inhibitors (ie Celexa, Paxil) and decongestants, may ... - Newark Star Ledger,

I Thank You  Jan 13, 2006
...to Wyeth-Ayerst Laboratories and Stuart Pharmaceuticals for further expanding that narrow channel of joy by manufacturing Effexor and Elavil; drugs so good ... - New York Times,

Your Health … Can’t seem to get your zzz’s? Stop suffering ...  Jan 9, 2006
...they cause drowsiness. These medications include Desyrel (trazadone), Elavil (amitriptyline), and Sinequan (doxepin). Often they ... - Valley City Times Record,

Prescription painkillers are gaining addicts -- and casualties  11 Dec 2005
Four more -- commonly known as Valium, Xanax, Soma and Elavil -- are generally prescribed for anxiety or depression, but also are used as pain treatments for ... - NewsOK.com (subscription),

Most Tolerable Antidepressant May Not be Most Efficacious  Dec 8, 2005
Prozac was better tolerated than any other antidepressant, most notably Elavil or Endep (amitriptyline) OR=0.64; 95% CI=0.47-0.85 and Tofranil (imipramine) OR ... - MedPage Today,

Experts say Prozac might not be the most effective antidepressant  Dec 8, 2005
...antidepressants. Patients found fluoxetine more tolerable than both Elavil or Endep (amitryptilline) and Tofranil (imipramine). ... - Dominican Today,

Prozac: Popular, but not potent?  Dec 7, 2005
...antidepressants. Patients found fluoxetine more tolerable than both Elavil and Endep (amitriptyline) and Tofranil (imipramine). ... - myDNA.com,

MEMBER EXCHANGE: Schizophrenic who killed parents strives for ...  Nov 27, 2005
During his 12 weeks at the center, Matt received intensive therapy and medication, including the powerful antipsychotic Navane and antidepressant Elavil. ... - Akron Beacon Journal,

Ask the Clinician: Answers to Readers' Questions  Oct 4, 2005
...was so intense... 4) I was diagnosed with migraines when I was five years old and took Elavil and Inderal until high school. I am ... - headaches.about.com

Chronic fatigue: Strictly biological?  Oct 3, 2005
In doses five to 10 times lower than those used for depression, tricyclic antidepressants such as Elavil can improve sleep, Komaroff says. ... - DetNews.com,

Creator of Valium Dies at 97  Sep 30, 2005
Its popularity presaged such tricyclic antidepressants as Elavil and Nardil in the 1980s, followed by the class of drugs that include Prozac, Zoloft and Paxil. ... - Washington Post,

Apple Cider Vinegar: Alternative Medicine Miracle  Sep 22, 2005
..."I was prescribed prednisone; methotrexate; hydroxyurea; several steroid ointments for topical therapy (too many to list), antibiotics and elavil for depression ... - SLCC Globe Link (subscription),

Many meds don't mix with the sun  Sep 21, 2005
Antidepressants: Amitriptyline (Elavil), amoxapine (Asendin), bupropion (Wellbutrin), citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin ... - Pioneer Press,

Chronic fatigue syndrome: a little-understood disease  Sep 9, 2005
In doses 10 percent to 20 percent as high as those used for depression, tricyclic antidepressants like Elavil can improve sleep, said Komaroff. ... - Baltimore Sun,

Childhood Depression Is Understudied and Under-treated  Sep 9, 2005
Although tricyclic antidepressants such as Elavil, selective serotonin reuptake inhibitors such as Prozac and Zoloft (sertraline) and specific norepinephrine ... - MedPage Today,

Antidepressants continue to be linked to suicidal thoughts  08 Sep 2005
They found that the SSRIs and tricyclics, such as Elavil, Norpramin, or Pamelor, had similar risk profiles with regard to suicide and self-harm in adults. ... - Pressbox.co.uk (press release),

Research clarifies true chronic fatigue  Sep 7, 2005
In doses 5 to 10 times lower than those used for depression, tricyclic antidepressants like Elavil can improve sleep, Komaroff said. ... - International Herald Tribune,

Acmemeds.com Improves Itself With 101 New Added Medications  Aug 20, 2005
...mg,Diprolene AF 0.05% 15 gm,Diprolene AF 0.05% 50 gm,Dovonex 0.005% 120 gm Ointment,Dovonex 0.005% 60 gm Cream,Dovonex 0.005% 60 gm Lotion,Elavil (generic) 10 ... - PR Web (press release),

Anxious cats and dogs  Aug 26, 2005
...this period. Available medications include antidepressants such as Clomical, Prozac or even Elavil. Consult your veterinarian. If ... - The Free Lance-Star,

The Summer He Didn't Die  Aug 13, 2005
After he sends nude pictures to their husbands, one of the women attempts to kill him by spiking his morning coffee with crushed Elavil. ... - San Francisco Chronicle,

"The Summer He Didn't Die": Novellas filled with humanity, wisdom  Aug 19, 2005
After suffering untold emotional abuse and betrayal, Martha, one of the wives, opts to put an end to her agony by dropping an overdose of Elavil into the ... - Seattle Times,

Best Treatments for Lasting Shingles Pain  Jul 25, 2005
Those shown effective for postherpetic neuralgia include nortriptyline (Pamelor), desipramine (Norpramin), and amitriptyline (Elavil, Endep). Strong opioids. ... - WebMD

Missoula inmates upset over medications  Jul 23, 2005
...was a teenager. Crane takes Paxil and Elavil for his condition, and regular doses are key to managing his symptoms. "The pills don ... - The Missoulian

Sleepwalking Can Be a Walk on the Wild Side  Jul 11, 2005
...behaviors drug therapy is indicated, with benzodiazepines such as Klonopin (clonazepam) or tricyclic antidepressants such as Elavil (amitriptyline) being the ... - MedPage Today <**results**>

Sleepwalking Can Be a Walk on the Wild Side  11 Jul 2005
...behaviors drug therapy is indicated, with benzodiazepines such as Klonopin (clonazepam) or tricyclic antidepressants such as Elavil (amitriptyline) being the ... - MedPage Today

Myers denied bail  Jul 2, 2005
He said he was taking antidepressants Lexapro and Elavil, and admitted to Michaels that he has a dependency on OxyContin, a prescription painkiller. ... - Phoenixville News

No escaping now  Jul 2, 2005
He said he was taking the antidepressants Lexapro and Elavil, and admitted to Michaels that he has a dependency on OxyContin, a prescription painkiller. ... - Chester Daily Local Online

More than Just Melancholy in Mothers-to-Be  Jun 30, 2005
...safe and effective for the mother and fetus during pregnancy: SSRIs, such as Prozac, Paxil, and Zoloft, and tricyclics, such as Elavil, Tofranil, and Pamelor ... - American Council on Science and Health,

Drugs Metabolized by P450 2D6 ¾ The biochemical activity of the drug metabolizing isozyme cytochrome P450 2D6 (debrisoquin hydroxylase) is reduced in a subset of the caucasian population (about 7-10% of caucasians are so called "poor metabolizers"); reliable estimates of the prevalence of reduced P450 2D6 isozyme activity among Asian, African and other populations are not yet available. Poor metabolizers have higher than expected plasma concentrations of tricyclic antidepressants (TCAs) when given usual doses. Depending on the fraction of drug metabolized by P450 2D6, the increase in plasma concentration may be small, or quite large (8-fold increase in plasma AUC of the TCA).

In addition, certain drugs inhibit the activity of this isozyme and make normal metabolizers resemble poor metabolizers. An individual who is stable on a given dose of TCA may become abruptly toxic when given one of these inhibiting drugs as concomitant therapy. The drugs that inhibit cytochrome P450 2D6 include some that are not metabolized by the enzyme (quinidine; cimetidine) and many that are substrates for P450 2D6 (many other antidepressants, phenothiazines, and the Type 1C antiarrhythmics propafenone and flecainide). While all the selective serotonin reuptake inhibitors (SSRIs), e.g., fluoxetine, sertraline, and paroxetine, inhibit P450 2D6, they may vary in the extent of inhibition. The extent to which SSRI-TCA interactions may pose clinical problems will depend on the degree of inhibition and the pharmacokinetics of the SSRI involved. Nevertheless, caution is indicated in the coadministration of TCAs with any of the SSRIs and also in switching from one class to the other. Of particular importance, sufficient time must elapse before initiating TCA treatment in a patient being withdrawn from fluoxetine, given the long half-life of the parent and active metabolite (at least 5 weeks may be necessary).

Concomitant use of tricyclic antidepressants with drugs that can inhibit cytochrome P450 2D6 may require lower doses than usually prescribed for either the tricyclic antidepressant or the other drug. Furthermore, whenever one of these other drugs is withdrawn from co-therapy, an increased dose of tricyclic antidepressant may be required. It is desirable to monitor TCA plasma levels whenever a TCA is going to be coadministered with another drug known to be an inhibitor of P450 2D6.

Monoamine Oxidase Inhibitors: Guanethidine or similarly acting compounds; thyroid medication; alcohol, barbiturates and other CNS depressants; and disulfiram

When amitriptyline HCl is given with anticholinergic agents or sympathomimetic drugs, including epinephrine combined with local anesthetics, close supervision and careful adjustment of dosages are required.

Hyperpyrexia has been reported when amitriptyline HCl is administered with anticholinergic agents or with neuroleptic drugs, particularly during hot weather.

Paralytic ileus may occur in patients taking tricyclic antidepressants in combination with anticholinergic-type drugs.

Cimetidine is reported to reduce hepatic metabolism of certain tricyclic antidepressants, thereby delaying elimination and increasing steady-state concentrations of these drugs. Clinically significant effects have been reported with the tricyclic antidepressants when used concomitantly with cimetidine. Increases in plasma levels of tricyclic antidepressants, and in the frequency and severity of side effects, particularly anticholinergic, have been reported when cimetidine was added to the drug regimen. Discontinuation of cimetidine in well-controlled patients receiving tricyclic antidepressants and cimetidine may decrease the plasma levels and efficacy of the antidepressants.

Caution is advised if patients receive large doses of ethchlorvynol concurrently. Transient delirium has been reported in patients who were treated with one gram of ethchlorvynol and 75 - 150 mg of amitriptyline HCl.