Desogestrel: profile and news
Ignorance, not faith, behind baby boom Feb 5, 2006
...should have informed choices and make their own decision," said Ballmer at the relaunching of the modern low-dose oral contraceptive Desogestrel 150 mcg ... - Journal Online,
Anti-pregnancy pill making a comeback Feb 2, 2006
Desogestrel, whose main ingredient is derived from the roots of a Mexican wild yam, is targeted at the female population (48.1 percent) that, according to the ... - INQ7.net,
Savient Pharmaceuticals, Inc. Announces Exploration of Strategic ... Feb 17, 2006
Savient's product Mircette(R) (desogestrel/ethinyl estradiol and ethinyl estradiol), an oral contraceptive, is marketed by its licensee, Duramed Pharmaceuticals ... - Genetic Engineering News,
Savient Pharmaceuticals, Inc. Announces Exploration of Strategic ... Feb 17, 2006
Savient's product Mircette(R) (desogestrel/ethinylestradiol and ethinyl estradiol), an oral contraceptive, is marketedby its licensee, Duramed Pharmaceuticals ... - Finanzen.net,
Cytogen and Savient Sign Letter of Intent for Marketing of ... Feb 8, 2006
Savient's product Mircette® (desogestrel/ethinyl estradiol and ethinyl estradiol), an oral contraceptive, is marketed by its licensee, Duramed Pharmaceuticals ... - Yahoo! News (press release)
Anti-pregnancy pill making a comeback Feb 2, 2006
Desogestrel, whose main ingredient is derived from the roots of a Mexican wild yam, is targeted at the female population (48.1 percent) that, according to the ... - INQ7.net,
Ignorance, not faith, behind baby boom Feb 5, 2006
...should have informed choices and make their own decision," said Ballmer at the relaunching of the modern low-dose oral contraceptive Desogestrel 150 mcg ... - Journal Online,
Cytogen and Savient Sign Letter of Intent for Marketing of ... Feb 8, 2006
Savient's product Mircette(R) (desogestrel/ethinyl estradiol and ethinyl estradiol), an oral contraceptive, is marketed by its licensee, Duramed Pharmaceuticals ... - PR Newswire (press release),
Birth Control Pills Can Cause Blood Clots Jan 30, 2006
Third-generation pills are more likely to cause problems, because they contain desogestrel, a different kind of hormone than older pills. ... - NBC 10.com,
Savient Pharmaceuticals Finalizes Agreement for the Settlement of ... Dec 2, 2005
...under the trade name Kariva(R). Under the terms of the transaction Barr will acquire the exclusive rights to Organon's Mircette (Desogestrel/Ethinyl Estradiol ... - PharmaLive.com (press release),
Barr, Organon and Savient Finalize Mircette(R) Settlement and ... Dec 1, 2005
...announced that Barr and its subsidiaries have finalized an agreement to acquire the exclusive rights to Organon's Mircette(R) (Desogestrel/Ethinyl Estradiol ... - Finanzen.net,
Organon to Settle Mircette Litigation with Duramed Sep 12, 2005
Mircette® (desogestrel/ethinyl estradiol and ethinyl estradiol) provides an oral contraceptive regimen of tablets each containing 0.15 mg desogestrel (13-ethyl ... - Patent Baristas,
Barr, Organon and Savient Announce Letter of Intent Regarding ... 08 Sep 2005
...and its subsidiaries have entered into a non- binding Letter of Intent to acquire the exclusive rights to Organon's Mircette(R) (Desogestrel/Ethinyl Estradiol ... - Finanzen.net,
First line of defence Aug 30, 2005
For example, in New Zealand the low-dose pill Mercilon (with 20µg ethinyloestradiol/150µg desogestrel) has been available for many years. ... - AustralianDoctor.com (subscription),
Watson Pharmaceuticals Receives FDA Approval for Desogestrel and ... Aug 1, 2005
...has received final approval from the United States (US) Food and Drug Administration (FDA) on its Abbreviated New Drug Application for desogestrel and ethinyl ... - PharmaLive.com (press release)
Movers & Shakers EBay, Guidant, Procter & Gamble Aug 1, 2005
Watson Pharmaceuticals Inc. (WPI: news, chart, profile) Monday said it received Food and Drug Administration approval for its desogestrel and ethinyl estradiol ... - MarketWatch
EBay, Guidant, Procter & Gamble and more Aug 1, 2005
Watson Pharmaceuticals Inc. (WPI) Monday said it received Food and Drug Administration approval for its desogestrel and ethinyl estradiol tablets, which ... - Investor's Business Daily (subscription)
Oral Contraceptive Shown to Fight Acne Jul 10, 2005
In the new study, Russian researchers found that a Pill regimen containing desogestrel, a synthetic version of the female hormone progesterone, reduced oily ... - PakTribune.com
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Oral Contraceptive Shown to Fight Acne 11 Jul 2005
In the new study, Russian researchers found that a Pill regimen containing desogestrel, a synthetic version of the female hormone progesterone, reduced oily ... - PakTribune.com
Contraception During Perimenopause Jun 22, 2005
The highest risk of venous thromboembolism is observed with preparations containing third-generation progestogens (desogestrel or gestodene)48. ... - RedNova.com,
Contraception During Perimenopause Jun 22, 2005
The highest risk of venous thromboembolism is observed with preparations containing third-generation progestogens (desogestrel or gestodene)48. ... - RedNova.com,
Some contraceptive pills also anti-acne Apr 1, 2005
...acne-free skin.". Gracial contains two female hormones: desogestrel (a progestogen) and ethynlestadiol (an estrogen). This pill has ... - INQ7 Interactive, Inc.,
Some contraceptive pills also anti-acne Apr 1, 2005
...acne-free skin.". Gracial contains two female hormones: desogestrel (a progestogen) and ethynlestadiol (an estrogen). This pill has ... - INQ7 Interactive, Inc.,
Other information
Indication
For the prevention of pregnancy in women who elect to use this product as a method of contraception.
Pharmacology
Desogestrel is used as a female contraceptive. Desogestrel is a progestin or a synthetic form of the naturally occurring female sex hormone, progesterone. In a woman's normal menstrual cycle, an egg matures and is released from the ovaries (ovulation). The ovary then produces progesterone, preventing the release of further eggs and priming the lining of the womb for a possible pregnancy. If pregnancy occurs, progesterone levels in the body remain high, maintaining the womb lining. If pregnancy does not occur, progesterone levels in the body fall, resulting in a menstrual period. Desogestrel tricks the body processes into thinking that ovulation has already occurred, by maintaining high levels of the synthetic progesterone. This prevents the release of eggs from the ovaries.
Mechanism Of Action
Binds to the progesterone and estrogen receptors. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once bound to the receptor, progestins like desogestrel will slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH (luteinizing hormone) surge.
Drug Category
Contraceptives, Oral, Synthetic; ATC:G03AC09
Brand Names/Synonyms
Cerazette; Cyclessa; DESOGESTREL; Desogen; Desogestrel; Desogestrel [Usan:Ban:Inn]; Desogestrelum [Inn-Latin]; HSDB 3593; Kariva; Mircette; ORG 2969; Org-2969, Cerazette; Ortho-Cept
Dosage Forms
TABLET
Absorption
Following oral administration, the relative bioavailability of desogestrel compared to a solution, as measured by serum levels of etonogestrel, is approximately 100%.
Interactions
-->Interactions for Desogestrel:
Reduced efficacy and increased incidence of breakthrough bleeding and menstrual irregularities have
been associated with concomitant use of rifampin. A similar association, though less marked, has been suggested with
barbiturates, phenyl-butazone, phenytoin sodium, carbamazepine and possibly with griseofulvin, ampicillin, and
tetracyclines (72).
Chemical IUPAC Name
13-ethyl-17-ethynyl-11-methylidene-1,2,3,6,7,8,9,10,12,13,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-ol
Chemical Formula
C22H30O
Half Life
27.8±7.2 hours
Drug Type
Approved Drug
# Accession No
APRD00762
CAS Registry Number
54024-22-5
