Desmopressin_acetate: profile and news

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Other information

Indication
For treatment of diabetes insipidus, prevention of polydipsia, polyuria and dehydration

Pharmacology
Increases plasma levels of Factor VIII in patients with mild hemophilia A and von Willebrands disease (Type 1). The cellular mechanism is not yet clear.

Mechanism Of Action
Binds to the vasopressin V2 receptor which leads to exocytosis from Weibel Palade bodies where both VWF and t-PA are stored, as well as to nitric oxide (NO) production via activation of endothelial NO synthase.

Drug Category
Antidiuretic Agents; pituitary (68:28.00)

Brand Names/Synonyms
Stimate

Dosage Forms
TABLET

Absorption
Not Available

Interactions
Not Available

Chemical IUPAC Name
Desmopressin acetate

Chemical Formula
C68H102N22O20S2

Half Life
Not Available

Drug Type
Approved Drug

# Accession No
BIOD00061

CAS Registry Number
16679-58-6