Delsym: profile and news

Area health care companies lend a hand to our economy Feb 26, 2006
...a Johnson & Johnson medical device company that employs 1,500 people in the area, and UCB Pharma Inc., which makes medicines such as Delsym cough suppressant ... - Rochester Democrat and Chronicle,

You Can`t Cure the Flu, but You Can Treat the Symptoms Feb 7, 2006
..."If it`sa dry nagging cough, you can take a cough suppressant, which would be dextromathorphan, and that`s in Robatussin DM or Delsym, Marshall says. ... - KQTV,

Business briefs Oct 28, 2005
...begins a seasonal direct marketing campaign today for Delsym, a cough suppressant developed in Rochester in the 1980s, to 65,000 US nurse practitioners ... - Rochester Democrat and Chronicle,

Disturbance leads to arrest Aug 4, 2005
Wells Place, and Bartosz Andrzejczyk, 18, of 85 Highpark Ave., allegedly took two boxes of cold pills, one wedge of Brie cheese and a bottle of Delsym and left ... - Stratford Star

Rx for a healthy medicine chest Apr 5, 2005
Cough: Try an oral decongestant or cough suppressant such as dextromethorphan. Or a timed-release cough syrup like Delsym. Stuffy ... - Detroit Free Press

UCB Pharma rents out office space at Jefferson Road site Mar 10, 2005
Former Celltech products, such as Tussionex, Delsym and Codeprex, all of which are cough medications, and Metadate CD, a drug for attention deficit disorder ... - Rochester Democrat and Chronicle,

Check medicines once a year Feb 17, 2005
Chloraseptic. Cough: Oral decongestant or cough suppressant such as dextromethorphan. Or a timed-release cough syrup like Delsym. Stuffy ... - SunHerald.com,

A healthy medicine cabinet Feb 14, 2005
Cough: Oral decongestant or cough suppressant such as dextromethorphan. Or a timed-release cough syrup like Delsym. • Stuffy ... - Charlotte Observer (subscription),

Other information

Indication
For treatment and relief of dry cough

Pharmacology
Suppresses the cough reflex by a direct action on the cough center in the medulla of the brain.

Mechanism Of Action
Dextromethorphan is an opioid-like drug that binds to and acts as antagonist to the NMDA glutamatergic receptor, it is an agonist to the opioid sigma 1 and sigma 2 receptors, it is also an alpha3/beta4 nicotinic receptor antagonist and targets the serotonin reuptake pump. Dextromethorphan is rapidly absorbed from the gastrointestinal tract, where it enters the bloodstream and crosses the blood-brain barrier. The first-pass through the hepatic portal vein results in some of the drug being metabolized into an active metabolite of dextromethorphan, dextrorphan, the 3-hydroxy derivative of dextromethorphan.

Drug Category
Antitussives; Analgesics; Antitussives; ATC:R05DA09

Brand Names/Synonyms
&Laquo;Delta&Raquo;-Methorphan; Antussan; Ba 2666; Balminil Dm; Balminil Dm Children; Benylin Adult Formula Cough Suppressant; Benylin Dm; Benylin Dm 12 Hour; Benylin Dm for Children; Benylin Dm for Children 12 Hour; Benylin Pediatric Cough Suppressant; Calmylin #1; Canfodion; Cosylan; Cough-X; Creo-Terpin; D-Methorphan; D-Methorphan Hydrobromide; Dea No. 9210; Delsym; Delsym Cough Formula; Delta-Methorphan; Demorphan; Demorphan Hydrobromide; Demorphine; Destrometerfano [Dcit]; Dextromethorfan; Dextromethorfan [Czech]; Dextromethorphan; Dextromethorphan Bromhydrate; Dextromethorphan Bromide; Dextromethorphan [Ban:Inn]; Dextrometorfano [Inn-Spanish]; Dextrometorphan; Dextromorphan; Dexyromethorphan; Diabe-Tuss Dm Syrup; Dormetan; Dormethan; Hihustan M.; Hold Dm; Koffex Dm; L-Methorphan; Levomethorphan; Levomethorphan [Ban:Dcf:Inn]; Levomethorphane [Inn-French]; Levomethorphanum [Inn-Latin]; Levometorfano [Inn-Spanish]; Medicon; Methorate Hydrobromide; Methorphan; Metrorat; Novahistex Dm; Novahistine Dm; Pertussin Cs Children's Strength; Pertussin Dm Extra Strength; Racemethorphan [As D-Form]; Robitussin Maximum Strength Cough Suppressant; Robitussin Pediatric; Robitussin Pediatric Cough Suppressant; Romilar; Sucrets 4 Hour Cough Suppressant; Triaminic Dm Long Lasting for Children; Trocal; Tusilan; Tussade; Vicks 44 Cough Relief

Dosage Forms
SYRUP

Absorption
Not Available

Interactions
Not Available

Chemical IUPAC Name
Not Available

Chemical Formula
C18H25NO

Half Life
Not Available

Drug Type
Approved Drug

# Accession No
APRD00655

CAS Registry Number
125-71-3