Capromab: profile and news

Positive Findings From Clinical Studies of QUADRAMET(R) in ... Feb 27, 2006
Cytogen's marketed products include QUADRAMET(R) (samarium Sm-153 lexidronam injection) and PROSTASCINT(R) (capromab pendetide) kit for the preparation of ... - International News Service,

Other information

Indication
For diagnosis of prostate cancer and detection of intra-pelvic metastases

Pharmacology
Binds to the prostate-specific membrane antigen, which is a cell surface protein generally overexpressed in prostate tissues and prostate cancers. The radioactive Indium 111, which is covalently attached to the antibody, allows radiodiagnostic detection of PSMA expressing cells and tumors

Mechanism Of Action
Binds selectively to cell-surface prostate-specific membrane antigen (PSMA) expressed on prostate tissues and tumors.

Drug Category
Imaging Agents

Brand Names/Synonyms
ProstaScint; ProstaScint (Cytogen Corp)

Dosage Forms
Not Available

Absorption
Not Available

Interactions
Not Available

Chemical IUPAC Name
Murine anti-7E11 antibody

Chemical Formula
Not Available

Half Life
Not Available

Drug Type
Approved Drug

# Accession No
BIOD00080

CAS Registry Number
145464-28-4