Botulinum_Toxin: profile and news
Botulinum Toxin Type A (Botox) Effective For Up to 2 Years in ... 06 Mar 2006
SAN FRANCISCO, CA -- March 6, 2006 -- Repeated botulinum toxin type A (Botox) injections for primary axillary hyperhidrosis is both safe and effective for up ... - DG News
SUFU 2006 - An Update on the Clinical Trials and Uses of Botulinum ... 06 Mar 2006
Botulinum toxin therapy represents an end organ or site specific treatment option for various neuromuscular dysfunctions. As a presynaptic ... - UroToday,
SUFU 2006 - Society for Urodynamics and Female Urology 2006 Winter ... 06 Mar 2006
In the "Botox as Pharmacomodulation" session the presentation on Botulinum Toxin for Lower Urinary Tract Dysfunction: Injection Techniques was given by Victor ... - UroToday,
PharmAthene wins 'orphan' approval for anthrax drug 06 Mar 2006
...pace of federal government efforts to order stockpiles of new medicines to treat potential bioweapons such as anthrax, smallpox, Botulinum toxin, Ebola and ... - Baltimore Business Journal,
New Head-to-Head Study Shows Longer Duration of Effect and Greater ... Mar 3, 2006
Doses - SAN FRANCISCO, March 3 /PRNewswire/ -- A new study comparing the efficacy and tolerability of two different formulations of botulinum toxin type A has ... - PR Newswire (press release),
New First-of-Its Kind Report Shows BOTOX(R) Cosmetic May Prevent ... Mar 3, 2006
A new case report comparing the appearance of facial lines in identical twins, one of whom received regular BOTOX® Cosmetic (botulinum toxin type A ... - Yahoo! News (press release)
Botox Could Help Target Resistant Tumors For Chemotherapy And ... Feb 20, 2006
..."Botulinum toxin could lead to inhibition ... Botulinum toxin is a naturally occurring molecule, and historically has been implicated with intestinal poisonings. ... - Medical News Today (press release),
‘Bush lied, you lied’ Mar 3, 2006
...groups like the Marsh Arabs. His bio arsenal was staggering-anthrax, botulinum toxin and dozens of others. His regime remains the ... - Village News Network,
Around South Florida Feb 25, 2006
The botulinum toxin was not approved by the US Food and Drug Administration for use on people and bore labels saying it was for research only, according to ... - Miami Herald,
DOR BioPharma Presents Positive New Survival Findings from Phase ... Feb 21, 2006
Our biodefense products in development are bioengineered vaccines designed to protect against the deadly effects of ricin toxin and botulinum toxin, both of ... - Genetic Engineering News,
Excessive Sweating in Teens Can Cause Physical and Emotional ... Mar 2, 2006
Strong, prescription anti-perspirants also may be combined with other treatments such as iontophoresis, surgery and botulinum toxin injections to help manage ... - PR Newswire (press release),
Concerns Over Vitamin C, Botox Injections From Dubious Sources Feb 12, 2006
Bandar Seri Begawan - There have been some concerns over a few women seeking beauty treatments like Vitamin C therapy and Botulinum Toxin (Botox) for wrinkles ... - Bru Direct,
Nip and tuck without hassles of major surgery Feb 27, 2006
Even though Botox is made from botulinum toxin A, which is a neurotoxin related to botulism -- a form of blood poisoning caused by food contaminated with the ... - El Paso Times,
FANATIC OR HERO? THE LIFE OF AN ANIMAL ACTIVIST Feb 27, 2006
In court Wickham said the mice were being legally used for tests on botulinum toxin (used in Botox) for a product used in the UK for therapeutic purposes to ... - The Western Gazette,
The genesis of a lie: How George Bush fabricated the Iraqi WMD ... Feb 21, 2006
...biological weapons sufficient to produce over 25,000 liters of anthrax," "materials sufficient to produce more than 38,000 liters of botulinum toxin," "as much ... - uruknet.info,
Antitoxin for infant botulism slashes hospital stays Feb 8, 2006
The illness usually occurs when babies swallow Clostridium botulinum spores, which grow in the large intestine and produce botulinum toxin. ... - CIDRAP,
CFIA: Health Hazard Alert-A & K Canned Sausages may Contain ... Feb 24, 2006
...consumption of this product. Food contaminated with Clostridium botulinum toxin may not look or smell spoiled. Consumption of food ... - CCNMatthews (press release),
The Miracle of Botox - An Introduction (Part 1) Feb 2, 2006
In the late 1970s, scientists discovered that botulinum toxin, when it was diluted to a great degree, had some very positive characteristics, properties that ... - Best Syndication,
Botox before the wrinkles Feb 20, 2006
Botox involves injecting small quantities of botulinum toxin into the facial area, paralysing facial muscles which produce wrinkles. ... - Sydney Morning Herald,
Mentor Reports Third Quarter Financial Results Feb 6, 2006
...the ongoing review of Mentor's pending silicone gel-filled breast implant Pre-Market Approval (PMA) application and the Company's botulinum toxin type A ... - Genetic Engineering News,
Deja Vu All Over Again Feb 22, 2006
2. The Intelligence -- Remember the good old days of aluminum tubes and those mobile bunkers churning out anthrax and botulinum toxin? ... - OpEdNews
What is esophageal spasm? Feb 16, 2006
Botulinum toxin (Botox) is also being used to treat esophageal spasm. Botulinum toxin is a poison produced by the bacteria that cause botulism. ... - IPP Media - Guardian,
Threat of bioterrorism is all about hype in US Feb 22, 2006
...people. Aum Shinrikyo failed in its attempts to obtain, produce and disperse anthrax and botulinum toxin between 1990 and 1994. ... - China Post,
Infant Botulism Drug Safe And Effective Feb 2, 2006
The drug is a lyophilized powder that contains about 5% human immune globulin with neutralizing antibodies against botulinum toxin types A and B -- the most ... - MedPage Today,
Botox Targets Resistant Tumors Feb 14, 2006
...(Ivanhoe Newswire) -- Botox, or Botulinum toxin, may have a new use as an adjuvant to cancer therapy, providing an open door for chemotherapy and radiation ... - Ivanhoe,
Botox aid against tumours Feb 15, 2006
..."Botulinum toxin could lead to inhibition of contractions of tumour vessels, improve tumour perfusion and oxygenation, and enhance the response of tumours to ... - Scenta.co.uk,
How To Reduce Perspiration | Stop Excessive Sweating Feb 18, 2006
...successfully are Iontophoresis where a low electrical current is introduced to the affected parts of the body or getting Botulinum toxin injections commonly ... - DailyIndia.com,
Doc on call Feb 15, 2006
The dystonia gene can be silent, and then something happens to set it off. Through medications, Botulinum Toxin (Botox) injections, and brain surgery. ... - Lucknow Newsline,
Medical Edge: Many drug options for migraines Feb 11, 2006
...headaches. In addition, botulinum toxin type A (Botox), currently in clinical trials for treatment of migraine, has shown promise. ... - Bryan College Station Eagle,
Beauty is more than skin deep, you cosmetic clowns Feb 4, 2006
Botox, otherwise known as botulinum toxin Type A, has a hair- raising provenance. It is one of the most lethal compounds known. ... - Stuff.co.nz,
Bugging the water Feb 4, 2006
...uses the highly sensitive water fleas to detect poisonous chemical and biological agents in their 13 reservoirs -- agents such as botulinum toxin, cyanide, VX ... - Pittsburgh Post Gazette,
William Rivers Pitt: The Wack-Pack Feb 14, 2006
The 26,000 liters of anthrax, the 38,000 liters of botulinum toxin, the 500 tons which is one million pounds of sarin, mustard and VX nerve agent, the 30,000 ... - Scoop.co.nz (press release),
Allergan Gets Past Estimates Feb 2, 2006
Pyott. In addition, Allergan increased the price of Botox by 4% to $485 per vial of the drug, also known as botulinum toxin A. Sales ... - TheStreet.com
"BIONOIA" Part 2 Jan 31, 2006
In the "golden years" of the 1950s and '60s, these secret facilities churned out tons —yes, tons—of "weaponized" anthrax, botulinum toxin, and our new ... - World War 4 Report,
Botox Treatments at Botox Parties may be Dangerous Jan 31, 2006
...been sentenced for 3 years in prison because the Botox was not the real thing; in error, he gave injections of live cultures of botulinum toxin which was ... - Best Syndication,
Allergan Reports Fourth Quarter Operating Results Feb 2, 2006
For full year 2005, therapeutic sales accounted for approximately 57% of total Botox(R) (botulinum toxin type A) sales and therapeutic sales grew at ... - Business Wire (press release),
The State of the Union Feb 1, 2006
State of the Union address, Mr. Bush told the nation that Iraq was in possession of 26,000 liters of anthrax, 38,000 liters of botulinum toxin, 500 tons (which ... - PeaceJournalism.com,
Other information
Indication
For treatment of cervical dystonia, axillary hyperhidrosis, strabismus, facial wrinkles
Pharmacology
Botox blocks neuromuscular transmission by binding to acceptor sites on motor or sympathetic nerve terminals, entering the nerve terminals, and inhibiting the release of acetylcholine. This inhibition occurs as the neurotoxin cleaves SNAP-25, a protein integral to the successful docking and release of acetylcholine from vesicles situated within nerve endings.
Mechanism Of Action
Not Available
Drug Category
Antidystonic Agents; Anti-Wrinkle Agents; unclassified therapeutic agents (92:00.00)
Brand Names/Synonyms
Botulinum neurotoxin type A precursor;BoNT/A;Bontoxilysin A;BOTOX[Contains: Botulinum neurotoxin A light- chain; Botulinum neurotoxin A heavy-chain]; BOTOX (Allegran Inc)
Dosage Forms
POWDER FOR SOLUTION
Absorption
Not Available
Interactions
Not Available
Chemical IUPAC Name
Not Available
Chemical Formula
C6760H10447N1743O2010S32
Half Life
Not Available
Drug Type
Approved Drug
# Accession No
BIOD00092
CAS Registry Number
Not Available