Beclovent: profile and news






Asthma Control May Be Weighty Matter  Feb 23, 2006
...like Singulair (montelukast) tend to have better control while leaner patients may do better with an inhaled steroid such as Beclovent (beclomethasone). ... - MedPage Today,

Body mass effects response to asthma medications  Feb 23, 2006
...with a type of inhaled steroid, while leaner people may have better luck with an inhaled steroid, called beclomethasone and sold as beclovent, vanceril and ... - Hindustan Times,

Obesity makes asthma harder to treat  Feb 22, 2006
The study said normal weight patients may have better luck with an inhaled steroid, called beclomethasone and sold as Beclovent, Vanceril and other brand names ... - United Press International <**results**>

Pharma Focus Now on Building Their Respiratory Portfolios  Jun 29, 2005
Major players like GlaxoSmithKline have pipeline products like Beconase (allergies), Becotide/Beclovent (asthma and chronic obstructive pulmonary disease ... - PharmaLive.com (press release),

Neuromed Technologies Expands Executive Team with the Addition of ...  May 12, 2005
...efforts of many major global brands including Effexor®, Protonix®, Altace®, Valtrex®, Zantac®, Flovent®, Flonase®, Serevent®, Beclovent® and Ventolin ... - PharmaLive.com

Attention Business Editors:  May 12, 2005
...efforts of many major global brands including Effexor(R), Protonix(R), Altace(R), Valtrex(R), Zantac(R), Flovent(R), Flonase(R), Serevent(R), Beclovent(R) and ... - Canada NewsWire,


Other information


Indication
For the maintenance treatment of asthma as prophylactic therapy in patients 5 years of age and older

Pharmacology
Beclomethasone, a synthetic halogenated glucocorticoid with antiinflammatory and vasoconstrictive effects, is used for treating steroid-dependent asthma, allergic or nonallergic rhinitis, or recurrent nasal polyps.

Mechanism Of Action
Unbound corticosteroids cross cell membranes and bind with high affinity to specific cytoplasmic receptors. The result includes inhibition of leukocyte infiltration at the site of inflammation, interference in the function of mediators of inflammatory response, suppression of humoral immune responses, and reduction in edema or scar tissue. The antiinflammatory actions of corticosteroids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.

Drug Category
Antiarrhythmic Agents; Glucocorticoids; Anti-inflammatory Agents; Corticosteroids; ATC:A07EA07; ATC:D07AC15; ATC:R01AD01; ATC:R03BA01

Brand Names/Synonyms
Aerobec; Aldecin; Anceron; Andion; Beclacin; Becloforte; Beclomet; Beclometasona [Inn-Spanish]; Beclometasondipropionat Mikron; Beclometasondipropionat Mikron.; Beclometasone; Beclometasonum [Inn-Latin]; Beclomethasone; Beclorhinol; Becloval; Beclovent; Becodisks; Beconase; Beconase Aq; Beconasol; Becotide; Clenil-A; Entyderma; Inalone; Korbutone; Propaderm; Qvar; Qvar 80; Rino-Clenil; Sanasthmax; Sanasthmyl; Vancenase; Vancenase Aq; Vanceril; Vanceril Double Strength; Viarex; Viarox

Dosage Forms
Oral inhalation; Nasal inhalation; Nasal Spray

Absorption
mean peak plasma concentration was 88pg/ml at 0.5 hour

Interactions
Interactions for Beclomethasone:
Albuterol, Antihistamines, antidiabetic drugs, diuretics, digitalis.

Chemical IUPAC Name
[9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate

Chemical Formula
C28H37ClO7

Half Life
2.8 hours

Drug Type
Approved Drug

# Accession No
APRD00564

CAS Registry Number
4419-39-0

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