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Beclovent: profile and news
Asthma Control May Be Weighty Matter Feb 23, 2006 Body mass effects response to asthma medications Feb 23, 2006 Obesity makes asthma harder to treat Feb 22, 2006 Pharma Focus Now on Building Their Respiratory Portfolios Jun 29, 2005 Neuromed Technologies Expands Executive Team with the Addition of ... May 12, 2005 Attention Business Editors: May 12, 2005 Other information Indication For the maintenance treatment of asthma as prophylactic therapy in patients 5 years of age and older Pharmacology Beclomethasone, a synthetic halogenated glucocorticoid with antiinflammatory and vasoconstrictive effects, is used for treating steroid-dependent asthma, allergic or nonallergic rhinitis, or recurrent nasal polyps. Mechanism Of Action Unbound corticosteroids cross cell membranes and bind with high affinity to specific cytoplasmic receptors. The result includes inhibition of leukocyte infiltration at the site of inflammation, interference in the function of mediators of inflammatory response, suppression of humoral immune responses, and reduction in edema or scar tissue. The antiinflammatory actions of corticosteroids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes. Drug Category Antiarrhythmic Agents; Glucocorticoids; Anti-inflammatory Agents; Corticosteroids; ATC:A07EA07; ATC:D07AC15; ATC:R01AD01; ATC:R03BA01 Brand Names/Synonyms Aerobec; Aldecin; Anceron; Andion; Beclacin; Becloforte; Beclomet; Beclometasona [Inn-Spanish]; Beclometasondipropionat Mikron; Beclometasondipropionat Mikron.; Beclometasone; Beclometasonum [Inn-Latin]; Beclomethasone; Beclorhinol; Becloval; Beclovent; Becodisks; Beconase; Beconase Aq; Beconasol; Becotide; Clenil-A; Entyderma; Inalone; Korbutone; Propaderm; Qvar; Qvar 80; Rino-Clenil; Sanasthmax; Sanasthmyl; Vancenase; Vancenase Aq; Vanceril; Vanceril Double Strength; Viarex; Viarox Dosage Forms Oral inhalation; Nasal inhalation; Nasal Spray Absorption mean peak plasma concentration was 88pg/ml at 0.5 hour Interactions Interactions for Beclomethasone: Albuterol, Antihistamines, antidiabetic drugs, diuretics, digitalis. Chemical IUPAC Name [9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate Chemical Formula C28H37ClO7 Half Life 2.8 hours Drug Type Approved Drug # Accession No APRD00564 CAS Registry Number 4419-39-0 |
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