Beclomethasone: profile and news
Weight May Influence Asthma Care 06 Mar 2006
MONDAY, March 6 (HealthDay News) -- Weight may have a bearing on asthma care: Researchers say beclomethasone, an inhaled steroid, may be better for normal ... - Forbes
Oral Beclomethasone Dipropionate Controls Gastrointestinal Graft ... Feb 21, 2006
HONOLULU, HI -- February 21, 2006 -- Oral beclomethasone dipropionate (BDP) appears to be effective in controlling gastrointestinal graft versus host disease ... - DG News
Singulair pill shows more promise for obese people Feb 23, 2006
...pill sold as Singulair than with a type of inhaled steroid, while leaner people may have better luck with an inhaled steroid, called beclomethasone and sold as ... - News-Medical.net,
DOR BioPharma Presents Positive New Survival Findings from Phase ... Feb 21, 2006
DOR BioPharma, Inc. (AMEX: DOR) ("DOR", or the "Company") announced today that survival results for orBec(R) (or oral beclomethasone dipropionate) from two ... - Genetic Engineering News,
DOR BioPharma Presents Positive New Survival Findings from Phase ... Feb 21, 2006
...(AMEX: DOR) ("DOR", or the "Company") announced today that survival results for orBec(R) (or oral beclomethasone dipropionate) from two randomized, double ... - Business Wire (press release),
Asthma Control May Be Weighty Matter Feb 23, 2006
...like Singulair (montelukast) tend to have better control while leaner patients may do better with an inhaled steroid such as Beclovent (beclomethasone). ... - MedPage Today,
Asthmatic's Weight Determines Medication Feb 26, 2006
...asthma have better results with the prescription pill Singulair, while lean people with asthma have better results with an the inhaled steroid beclomethasone. ... - Ivanhoe,
Obesity makes asthma harder to treat Feb 22, 2006
The study said normal weight patients may have better luck with an inhaled steroid, called beclomethasone and sold as Beclovent, Vanceril and other brand names ... - United Press International
orBec® Improves Survival in Patients with Intestinal Graft-Versus ... Feb 21, 2006
...the 2006 annual Tandem Bone Marrow Transplant Meeting of the American Society of Hematology, the oral agent orBec® (oral beclomethasone dipropionate) improves ... - Cancer Consultants (press release),
Generic Pharmaceutical Association Feb 17, 2006
...albuterol). Ipratropium, beclomethasone and numerous other products are on the market without patent or exclusivity protection. ... - FDA.gov
DOR BioPharma Provides Financial Guidance and Update on European ... Feb 8, 2006
Our lead product, orBec(R) (oral beclomethasone dipropionate), is a potent, locally-acting corticosteroid being developed for the treatment of intestinal Graft ... - Genetic Engineering News,
New Guidelines Released for Managing Cough Feb 14, 2006
...chest radiographs and spirometry (if age appropriate) for children with chronic cough; and a short trial (2 to 4 weeks) of beclomethasone or budesonide for ... - Journal of American Medical Association (subscription),
Refractory Asthma May Respond to TNF-Alpha Inhibition Feb 16, 2006
...markers of TNF-alpha activity on peripheral-blood monocytes in 10 patients with refractory asthma (for whom the daily dose of inhaled beclomethasone or its ... - Medscape (subscription)
DOR BioPharma Provides Financial Guidance and Update on European ... Feb 8, 2006
Our lead product, orBec(R) (oral beclomethasone dipropionate), is a potent, locally-acting corticosteroid being developed for the treatment of intestinal Graft ... - Genetic Engineering News,
DOR BioPharma Reports Positive New Survival Findings from ... Jan 20, 2006
...or the "Company") announced today that as part of its process to submit a New Drug Application ("NDA") for orBec(R) (oral beclomethasone dipropionate) for the ... - Business Wire (press release),
Breathe Deep Jan 20, 2006
...professor in the Department of Clinical Sciences and head of equine medicine and surgery, is investigating the efficacy of beclomethasone dipropionate for ... - TheHorse.com,
Breathe Easier! Jan 22, 2006
...with inhaled steroids. Two studies published in 1998 reported on aerosolized beclomethasone for heavey horses. The results were ... - TheHorse.com,
Beximco Pharma begins exporting medicines to Sri Lanka Jan 20, 2006
The four generics of exported drugs are Azithrocin (Azithromycin), Decomit (Beclomethasone dipropionate), Cox B (celecoxib) and Deflux (Domperidone). ... - The New Nation,
Allergic rhinitis key to asthma control Dec 10, 2005
Stelmach and colleagues evaluated the effects of treatment with inhaled or topical nasal beclomethasone dipropionate (BDP), a steroid, given separately or in ... - Sydney Morning Herald (subscription),
DOR BioPharma Maintains AMEX Listing Dec 10, 2005
Our lead product, orBec(R) (oral beclomethasone dipropionate), is a potent, locally-acting corticosteroid being developed for the treatment of intestinal Graft ... - NAMC Newswire Releases (press release),
Rigel Announces Disappointing Results from Phase II Study of R112 ... Dec 1, 2005
The randomized, double-blind study compared R112 and Beconase AQ(R) (beclomethasone) nasal spray to placebo, over a 7-day period. ... - PR Newswire (press release),
Rigel allergy drug fades in Phase 2 trial Dec 1, 2005
Rigel said it was testing the drug in a 396-patient, randomized, double-blind study comparing R112 and Beconase (beclomethasone) to placebo over a seven-day ... - United Press International
Dr. Chris Dale, Vice President, Technology, Cambrex ... Sep 15, 2005
Their lead product, orBec(R) (oral beclomethasone dipropionate), is a potent, locally-acting corticosteroid being developed for the treatment of intestinal ... - PR Newswire (press release),
Inyx Updates Financial Guidance for 2005 and 2006 Sep 13, 2005
Inyx's initial proprietary products include: * "Beclomethasone" (generic steroid name) used as an anti-inflammatory nasal spray for the treatment of allergy ... - PR Newswire (press release),
Nasal Sprays Sep 24, 2005
Vancenase and Beconase (beclomethasone), Nasarel (flunisolide), Rhinocort (budesonide), Nasonex (mometasone), and Flonase (fluticasone), to name a few, can get ... - allergies.about.com
How do you spell relief for what ails you? Sep 14, 2005
...for asthma, rheumatoid arthritis, colitis, skin disorders, and immune disorders): Prednisone, hydrocortisone, desamethasone, beclomethasone, and triamcinolone ... - Cochrane Times,
A Review of Pregnancy Outcomes After Exposure to Orally Inhaled or ... Aug 12, 2005
In pregnant women with asthma, use of inhaled budesonide or beclomethasone has been shown to reduce the incidence of acute asthma exacerbations (4% of patients ... - RedNova.com,
FDA Approvals: Invader UGT1A1, SelectSecure Model 3830, Duet ... Aug 26, 2005
The lead also releases beclomethasone dipropionate for a short while after implantation to reduce postimplantation inflammation and improve tissue conduction. ... - Medscape (subscription)
Comparative Phase II Clinical Trial of R112 for Allergy Treatment Aug 10, 2005
...to enroll approximately 375 patients, will be a randomized, double-blind study comparing R112 to placebo and Beconase AQ(R) (beclomethasone) nasal spray over a ... - Medical News Today (press release),
When an Asthma Drug Has an Inferiority Complex: A Noninferiority ... Aug 14, 2005
...review (last substantive update, October 2003) concluded that for adults, "[i]nhaled steroids at a dose of 400 meg/ day of beclomethasone or equivalent are ... - RedNova.com,
DOR BioPharma and Dowpharma Enter Into a Joint Development ... Jul 26, 2005
Our lead product, orBec® (oral beclomethasone dipropionate), is a potent, locally-acting corticosteroid being developed for the treatment of intestinal Graft ... - Yahoo News (press release)
<**results**>
Vaccine Researchers Combat Biothreat Agents; Preclinical Safety ... Jul 5, 2005
DOR's lead therapeutic product, orBec(R) (oral beclomethasone dipropionate), is a potent, locally-acting corticosteroid being developed for the treatment of ... - Business Wire (press release)
DOR BioPharma to Present at the Rodman & Renshaw Techvest 2nd ... Jun 13, 2005
Our lead product, orBec(R) (oral beclomethasone dipropionate), is a potent, locally-acting corticosteroid being developed for the treatment of intestinal Graft ... - Business Wire (press release),
Other information
Indication
For the maintenance treatment of asthma as prophylactic therapy in patients 5 years of age and older
Pharmacology
Beclomethasone, a synthetic halogenated glucocorticoid with antiinflammatory and vasoconstrictive effects, is used for treating steroid-dependent asthma, allergic or nonallergic rhinitis, or recurrent nasal polyps.
Mechanism Of Action
Unbound corticosteroids cross cell membranes and bind with high affinity to specific cytoplasmic receptors. The result includes inhibition of leukocyte infiltration at the site of inflammation, interference in the function of mediators of inflammatory response, suppression of humoral immune responses, and reduction in edema or scar tissue. The antiinflammatory actions of corticosteroids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.
Drug Category
Antiarrhythmic Agents; Glucocorticoids; Anti-inflammatory Agents; Corticosteroids; ATC:A07EA07; ATC:D07AC15; ATC:R01AD01; ATC:R03BA01
Brand Names/Synonyms
Aerobec; Aldecin; Anceron; Andion; Beclacin; Becloforte; Beclomet; Beclometasona [Inn-Spanish]; Beclometasondipropionat Mikron; Beclometasondipropionat Mikron.; Beclometasone; Beclometasonum [Inn-Latin]; Beclomethasone; Beclorhinol; Becloval; Beclovent; Becodisks; Beconase; Beconase Aq; Beconasol; Becotide; Clenil-A; Entyderma; Inalone; Korbutone; Propaderm; Qvar; Qvar 80; Rino-Clenil; Sanasthmax; Sanasthmyl; Vancenase; Vancenase Aq; Vanceril; Vanceril Double Strength; Viarex; Viarox
Dosage Forms
Oral inhalation; Nasal inhalation; Nasal Spray
Absorption
mean peak plasma concentration was 88pg/ml at 0.5 hour
Interactions
Interactions for Beclomethasone:
Albuterol, Antihistamines, antidiabetic drugs, diuretics, digitalis.
Chemical IUPAC Name
[9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
Chemical Formula
C28H37ClO7
Half Life
2.8 hours
Drug Type
Approved Drug
# Accession No
APRD00564
CAS Registry Number
4419-39-0