Alesse: profile and news






Group supporting workers' comp changes says they will benefit ...  Mar 1, 2006
Mark Alesse, state director of the National Federation of Independent Business, said the state AFL-CIO is opposing making significant changes in the system ... - Albany Business Review,

Business Organizations Mount Campaign for Overhaul of Workers' ...  Mar 3, 2006
Gilroy was joined by Mark Alesse, state director of the National Federation of Independent Businesses, and Elliott Shaw, director of government affairs for the ... - Texas Lawyer (subscription),

Haverhill, North Reading primed for run  Feb 27, 2006
The Raiders will also count upon sophomore goalie Mike Alesse, who tied for the area lead with four shutouts and closed out the season with a 36-save effort ... - Eagle Tribune,

Modern medicine will kill us all  Feb 1, 2006
...of modern methods of childbirth. Please don’t worry. I’m not pregnant; I’m on Alesse. Anyways, because humans walk upright ... - Gateway.ualberta.ca,

Modern medicine will kill us all  Feb 1, 2006
...of modern methods of childbirth. Please don’t worry. I’m not pregnant; I’m on Alesse. Anyways, because humans walk upright ... - Gateway.ualberta.ca,

State’s minimum wage hike impacts 1,780 county workers  Jan 8, 2006
...increase. Paying higher wages does not reduce the cost of doing business in New York, stated Mark Alesse, the federation’s director. ... - Olean Times Herald,

Reading in hunt to repeat success  11 Dec 2005
...junior Kevin McCarron. Two sophomores, Justin Bolognese and Mike Alesse, will try to win the job in goal. Fourteen-year Billerica ... - Boston Globe,

Danny Glover serves up star power to ethnic workers weighed down ...  Dec 7, 2005
Ads like this one for Alesse (top) promote brand without explaining side effects, while herpes and cholesterol ads hide corporate connections. ... - Now Toronto,

Central hockey opens with romp in Vermont tourney  Dec 10, 2005
It was Smith's first-ever goal as a varsity player. Justin Kurek also had a couple of assists, and goalie Mike Alesse stopped 18 of 19 shots. ... - Lowell Sun,

First Lady Patti Blagojevich receives Pro-Choice Leadership Award ...  Dec 7, 2005
...prescription drugs are now available through I-Save Rx, including Ortho-Evra 20-150, Ortho Novum 7/7/7, Ortho-Cyclen, Ortho Tri-Cyclen, Alesse, Micronor and ... - IGNN (press release),

Find Out What Homes Are Selling For In Your Area. - Romania ...  Nov 24, 2005
...ingredients ortho drug fishy southern prescription kroger hydrocodone college tmj online pharmacy order anabolic morphine link canadarx alesse lorcet online ... - �庆�年报,

Health Watch  Sep 14, 2005
...needs. We carry many brands of birth control pills (Alesse, Cyclessa, Mircette, Nordette, OrthoTriCyclen Lo), priced at $15 per pack. ... - Informer (subscription),

Businesses in NY face another tax hike  Sep 22, 2005
...tax. the country," said Mark Alesse, director of the New York state chapter of the National Federation of Independent Business. ... - Oneonta Daily Star,

Drive on to increase minimum wage  Sep 6, 2005
...will either raise prices of their products or fire employees to cover costs," said local National Federation of Independent Businesses spokesperson Mark Alesse ... - Troy Record,

Cancer drug plus the Pill relieves endometriosis  Aug 26, 2005
...study the investigators treated 18 women, who had failed at least two other treatments for endometriosis, with anastrozole and the Alesse oral contraceptive ... - Reuters.uk,

Why New York State Has The Worst Workers' Comp In The Nation  Jul 13, 2005
...driver in New York and the reason employers' workers' compensation costs are about 20 percent higher than the national average," says Mark Alesse, New York ... - LongIslandPress.com

Bill appeals to businesses: Stay at home  Jul 28, 2005
..."It's well-intentioned, but not the kind of comprehensive approach (the state needs)," said Mark Alesse, state coordinator of the National Federation of ... - Press & Sun-Bulletin

Mrs. Blagojevich also announces that seven contraceptives are now ...  Jul 13, 2005
Prescription contraceptives, such as Ortho-Evra 20-150, Ortho Novum 7/7/7, Ortho-Cyclen, Ortho Tri-Cyclen, Alesse, Micronor and Triphasil are available from ... - Illinois Government News Network

Bill appeals to businesses: Stay at home  Jul 28, 2005
..."It's well-intentioned, but not the kind of comprehensive approach (the state needs)," said Mark Alesse, state coordinator of the National Federation of ... - Press & Sun-Bulletin,

Why New York State Has The Worst Workers' Comp In The Nation  Jul 13, 2005
...driver in New York and the reason employers' workers' compensation costs are about 20 percent higher than the national average," says Mark Alesse, New York ... - LongIslandPress.com,

Mrs. Blagojevich also announces that seven contraceptives are now ...  Jul 13, 2005
Prescription contraceptives, such as Ortho-Evra 20-150, Ortho Novum 7/7/7, Ortho-Cyclen, Ortho Tri-Cyclen, Alesse, Micronor and Triphasil are available from ... - Illinois Government News Network,

The Desert-Mountain Times  Apr 20, 2005
Discus: 1. Amanda Baker, Crane, 123-8; 2. Alesse Chisum, Crane, 116-3; 3. Tiffany Bagwell, Crane, 94-6; 4. Cassie Aguilar, 78-10; 5. Stephanie Zavala, Tornillo ... - The Desert-Mountain Times

Colo. considers NY health plan to help small biz  Apr 11, 2005
..."For the folks that qualify, it's a great program," said Mark Alesse, the New York director for the National Federation of Independent Business (NFIB). ... - Denver Business Journal

INSIDE BUSINESS  Apr 10, 2005
However, Mark Alesse, state director for the National Association of Independent Business, said that while the board setting rates for the insurance companies ... - Newsday,

Small biz owners find little help from state  Mar 2, 2005
..."All are too high and make us uncompetitive," said Mark Alesse, director of the NFIB's New York office. Government officials have ... - Buffalo Business First,

Small firms rate New York  Mar 4, 2005
..."Our economy can't get out of first gear because we have the highest overall costs of doing business in the nation," Mark Alesse said. ... - Rochester Democrat and Chronicle,

Growth in Retail Prescriptions Slows in 2004  Mar 7, 2005
17 ADALAT XL Anti-hypertensive 2,590 4.5 ----- 18 ALESSE Oral contraceptive 2,496 12.9 ... - Canada NewsWire (press release),

Bill would make firms notify customers in identity theft cases  Mar 7, 2005
Mark Alesse, director of the New York chapter of the National Federation of Independent Business, said his group has a national database of 500,000 members. ... - MSNBC

Pataki expected to push SPUR program  Feb 15, 2005
..."Programs like SPUR can possibly be of some utility in some communities, and we're optimistic that they will be," said Mark Alesse, director of the National ... - Buffalo News,

Contraceptives, antidepressants, acne meds top campus drug plans  Mar 3, 2005
...most at McGill University, the University of Saskatchewan and the University of British Columbia are brands like Tri-Cyclen, Marvelon and Alesse, while anti ... - Gateway.ualberta.ca,


Other information


Indication
For treatment of moderate to severe vasomotor symptoms associated with the menopause, female hypogonadism, prostatic carcinoma-palliative therapy of advanced disease, breast cancer, as an oral contraceptive, and as emergency contraceptive.

Pharmacology
Ethinyl estradiol is a synthetic derivative of the natural estrogen estradiol. It is one of two estrogens currently used in oral contraceptive pills. The other, mestranol, is converted to ethinyl estradiol before it is biologically active. Ethinyl estradiol and norethindrone are used together as an oral contraceptive agent.

Mechanism Of Action
Estrogens diffuse into their target cells and interact with a protein receptor. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Estrogens increase the hepatic synthesis of sex hormone binding globulin (SHBG), thyroid-binding globulin (TBG), and other serum proteins and suppress follicle-stimulating hormone (FSH) from the anterior pituitary. The combination of an estrogen with a progestin suppresses the hypothalamic-pituitary system, decreasing the secretion of gonadotropin-releasing hormone (GnRH).

Drug Category
Estrogens; ATC:G03CA01

Brand Names/Synonyms
17?-Ethynylestradiol; 17alpha-Ethinylestradiol; 17alpha-Ethynylestradiol; 17alpha-Ethynyloestradiol; Aethinyloestradiolum; Aethinyoestradiol [German]; Alesse; Alora; Amenoron; Amenorone; Anovlar; BRN 2419975; Binovum; Brevicon; Brevinor; CCRIS 286; CHEMBANK1139; Climara; Conceplan; Cyclosa; Demulen; Desogen; Dicromil; Diognat-E; Diogyn E; Diogyn-E; Diprol; Dyloform; EE; EE2; EO; ETHINYLESTRADIOL; Ertonyl; Esclim; Esteed; Estigyn; Estinyl; Eston-E; Estopherol; Estoral; Estoral {[Orion]}; Estorals; Estrace; Estraderm; Estradiol; Estring; Estrogel; Estrogen; Ethidol; Ethinoral; Ethinyl Estradiol; Ethinyl-Oestranol; Ethinylestradiolum [Inn-Latin]; Ethinylestriol; Ethinyloestradiol; Ethy 11; Ethynylestradiol; Ethynyloestradiol; Eticyclin; Eticyclol; Eticylol; Etinestrol; Etinestryl; Etinilestradiol [Inn-Spanish]; Etinilestradiolo [Dcit]; Etinoestryl; Etistradiol; Etivex; Feminone; Fempatch; Follicoral; Genora; Ginestrene; Gynodiol; Gynolett; HSDB 3587; Halodrin; Inestra; Innofem; Jenest; Kolpolyn; Levlen; Linoral; Lo/Ovral; Loestrin; Logynon; Lynoral; Marvelon; Menolyn; Menostar; Mercilon; Microfollin; Microgynon; Mircette; Modicon; NEE; NSC-10973; Necon; Nelova; Neo-Estrone; Neocon; Nogest-S; Norcept; Nordette; Norethin 1/35 E; Norimin; Norinyl; Norlestrin; Novestrol; Oradiol; Orestralyn; Orestrayln; Ortho Tri-Cyclen; Ortho-Cept; Ortho-Cyclen; Ortho-Novum; Ovcon; Ovex; Oviol; Ovral; Ovran; Ovranette; Ovysmen; Palonyl; Perovex; Primogyn; Primogyn C; Primogyn M; Progynon C; Progynon M; Prosexol; Spanestrin; Stediril; Synphase; Tetragynon; Thiuram E; Thiuranide; Tri-Levlen; Tri-Norinyl; Trinordiol; Trinovum; Triphasil; Vagifem; Varnoline; Vivelle; Ylestrol

Dosage Forms
DISC (SUSTAINED-RELEASE); GEL; IMPLANT; LIQUID; PATCH; RING (SLOW-RELEASE); SOLUTION; TABLET

Absorption
Rapid and complete absorption follows oral intake of ethinyl estradiol (bioavailability 43%).

Interactions
Drug Interactions for Ethinyl Estradiol:

Certain endocrine and liver function tests may be affected by estrogen-containing oral contraceptives. The following similar changes may be expected with larger doses of estrogen:

Increased sulfobromophthalein retention; increased prothrombin and factors VII, VIII, IX, and X; decreased antithrombin 3; increased norepinephrine-induced platel et aggregation; increased thyroid binding globulin (TBG) leading to increased circulating total thyroid hormone, as measured by PBI, T4 by column, or T4 by radioimmunoassay. Free T3 resin uptake is decreased, reflecting the elevated TBG; free T4 concentration is unaltered: impaired glucose tolerance; decreased pregnanediol excretion; reduced response to metyrapone test; reduced serum folate concentration; increased serum triglyceride and phospholipid concentration.



Chemical IUPAC Name
17-ethynyl-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol

Chemical Formula
C20H24O2

Half Life
36 +/- 13 hours

Drug Type
Approved Drug

# Accession No
APRD00691

CAS Registry Number
57-63-6

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