Adenosine: profile and news
Lyons to spearhead PCE Investors’ capital raising efforts 07 Mar 2006
PCE Investors, the London-based investment management platform, has appointed Lorraine Lyons to spearhead capital raising for its managers. ... - HedgeWeek,
FACTBOX-Fed views on US inflation targeting 07 Mar 2006
He has said a 1 percent to 2 percent increase in the core price index for personal consumption expenditures (PCE price index) would be an optimal US inflation ... - Reuters
Contamination cleanup plans 07 Mar 2006
...in 1993 showed the presence of two chemical solvents, trichloroethylene, or TCE, and tetrachloroethene, (also called perchloroethylene, or PCE) and their ... - The Journal News.com,
NASA Space Station On-Orbit Status 6 March 2006 07 Mar 2006
FE Tokarev meanwhile installed electronic components for the scheduled end-to-end testing of the ATV PCE (Automated Transfer Vehicle/Proximity Communications ... - Space Ref
How Treasury Yields Might Reach 5.25% 07 Mar 2006
A slow creep upward in core inflation also has been a factor, given that the PCE deflator is trending above 2.0%, above the Fed's target for a pace of no ... - TheStreet.com (subscription),
Treasuries buoyed as core PCE retreats on year Mar 1, 2006
NEW YORK, March 1 (Reuters) - Short-term US Treasury debt prices edged higher on Wednesday after the Federal Reserve's favored measure of inflation eased on a ... - Reuters
PCE Deflator Jumps in January Mar 1, 2006
As expected, an uptick in energy prices was enough to push the PCE deflator up 0.5%, its largest increase since September's Katrina-provoked spike. ... - The Dismal Scientist (subscription),
Bloggers co-opted for PR Mar 6, 2006
...``I'ma small-business person like you,'' Zimmer told the PCE members. ... PCE member Michelle Howe of Word Magic, an Internet copywriter, agreed. ... - Akron Beacon Journal,
Micro-business forum for military spouses set Mar 3, 2006
Philippine Center for Entrepreneurship, said the forum would be held at the Army gymnasium in Fort Bonifacio as part of a range of activities the PCE had lined ... - TMCnet
Testing the waters Mar 3, 2006
The EPA found five contaminants in groundwater - tetrachloroethene (PCE), trichloroethene (TCE), 1,1,2-trichloroethane (TCA), styrene and touene. ... - North Platte Telegraph,
FOREX-Dollar regains footing on US manufacturing data Mar 1, 2006
The core personal consumption expenditure index (PCE) -- a gauge the Federal Reserve watches closely -- rose 0.2 percent in January, in line with forecasts. ... - Reuters.uk,
Pacific Asia China Energy Inc. Receives Approval of Asia Canada ... Mar 1, 2006
...("PCE") (TSX VENTURE:PCE ... ("ACE"). As a result of this approval, PCE will proceed on closing the transaction (See Exchange Bulletin dated February 28, 2006). ... - CCNMatthews (press release),
Top Market Movers Feb 28, 2006
As a result, bulls are looking ahead to another full slate of data in countering today's move. Of note will the PCE Core and manufacturing data. ... - AME Info,
FOREX-Dollar trims gains against yen, rate view holds Feb 28, 2006
The GDP report showed inflation as measured by its price index for consumer spending -- the personal consumption expenditures index, or PCE -- ticked up more ... - Reuters.uk,
US Treasuries up as GDP inflation gauge trimmed Feb 28, 2006
Within the GDP data, the core PCE price index, the Fed's favorite measure of inflation that strips out food and energy costs, increased at a 2.1 percent rate ... - Reuters
January consumer spending surges, saving dips Mar 1, 2006
When volatile food and energy costs are stripped out, the so-called core PCE price index rose a milder 0.2 percent, in line with forecasts, up from a 0.1 ... - Washington Post,
Bond Brief: Mixed Results Mar 1, 2006
...expectations for a 0.6% gain. Moreover, one of the Federal Reserve's favorite inflation gauges, the core PCE price index, softened year-on-year. ... - TheStreet.com
US Treasuries ease as corporate hedging takes toll Feb 27, 2006
...market on Wednesday will be scouring through the Fed's favorite inflation measure -- the core Personal Consumption Expenditures price index (PCE) -- along with ... - Reuters
Dollar Propped by ISM Mar 1, 2006
US economic data released today included January personal income, personal spending, personal saving, PCE price index, construction spending, and manufacturing ... - Forex Market,
Personal Incomes Increase 0.7% in January Mar 1, 2006
Personal consumption expenditures (PCE) increased $76.7 billion, or 0.9 percent. In December, personal income increased $54.8 billion ... - 123Jump.com,
In US January Spending Outpaces Income Mar 1, 2006
March 1, 2006 -- Consumers kept up their spending ways in January, with personal consumption expenditures (PCE) rising nine-tenths of a percentage point, just ... - Industry Week
GLOBAL MARKETS-European stocks fight back, dollar languishes Mar 1, 2006
1330 GMT is the personal income and spending report -- and the key inflation reading it contains, the core personal consumption expenditure, or PCE, price index ... - FXstreet.com The Futures Market,
Pressure on Dollar Continues Mar 1, 2006
PCE deflator rose by 3.1% annual but core PCE deflator slowed and was up 1.8% only, comparing to 1.9% in each of the three preceding months. ... - ForexTV.com,
Metals...From Goldseek Mar 1, 2006
Core PCE rose 0.2% in January and grew at 1.8% year over year. This was considered to be tame inflation-wise. The savings rate was ... - eTV Futures,
Gov't agency sets fund for entrepreneurs Feb 27, 2006
...billion that will be loaned to entrepreneurs, the government lending agency, has also tied up with the Philippine Center for Entrepreneurship (PCE) which will ... - Philippine Information Agency,
Income Rises, Savings Rate Sinks Mar 1, 2006
1.9% in December. The Federal Reserve watches the core PCE price index closely for signs of excessive inflation. The central bank's ... - Smartmoney.com
USD Slumps on Weak Data Feb 28, 2006
...previous quarter. The preliminary GDP deflator was also up 3.3%, versus 3.0% and the PCE price index was up 2.7%, from 2.6%. The ... - Forex Market,
FX Markets Today Mar 1, 2006
The Fed's preferred inflation indicator, the core PCE deflator, also came in as expected, which is unlikely to alter interest rate expectations. ... - ForexTV.com,
US consumer spending surges in Jan, saving dips Mar 1, 2006
When volatile food and energy costs are stripped out, the so-called core PCE price index rose a milder 0.2%, in line with forecasts, up from a 0.1% increase ... - Gulf Times,
Dollar drifts higher on ISM Mar 1, 2006
In early afternoon trading, the euro was down 0,1% at $1,1903, drifting back down from session highs around $1,1970 following the release of the PCE data. ... - Business Day,
Euro Slightly Lower on Dollar Strength Feb 27, 2006
Traders are looking to the manufacturing numbers as well as the Fed’s favored inflation gauge, PCE, for any upside surprises that may raise expectations of a ... - Daily FX,
Downward pressure on gold Feb 28, 2006
...session. We've got a host of US data out," he continued. He explained that the GDP and PCE deflators were both due out. Both allude ... - iAfrica.com,
New Data Support 5% GDP Call Mar 1, 2006
...current quarter. The PCE deflator rose 0.2% for the fifth time in six months, which puts the rate above the Fed's target range. The ... - TheStreet.com (subscription),
Foruth-Quarter GDP Revised Upward Feb 28, 2006
Although the price deflator was revised upward to show a 3.3% gain instead of 3.0%, the PCE core deflator was revised downward to a 2.1% gain from 2.2%. ... - TheStreet.com (subscription),
Business economists say US economy will roar back in first quarter ... Feb 26, 2006
When asked to identify what they believed are the Fed’s long-run inflation objectives for the core CPI and core PCE price index, the panel’s mean responses ... - FinFacts Ireland,
State tests for solvent vapors Feb 23, 2006
Laundry on Court Street. They are testing for perchlorethylene, or PCE, and trichloroethylene, or TCE, among others. Onslow County Tax ... - Jacksonville Daily News,
Small business can take advantage of Web log explosion Feb 20, 2006
PCE member Michelle Howe of Word Magic, an Internet copywriter, agreed. One of her articles went out on a blog, and she got a new client in Florida. ... - Lansing State Journal,
RP entrepreneurs are patriots GMA Feb 23, 2006
Speaking at the summit called by the Philippine Center for Entrepreneurship (PCE), the President said company executives were more bullish about the economy ... - TMCnet
Water well shut down after toxin level rises Feb 7, 2006
Authority last month shut down a well that served about 1,000 Barrigada customers because too much of chemical tetrachloroethylene, or PCE, was found in the ... - Pacific Daily News,
EPA says cleanup complete at Fargo dry cleaner site Feb 22, 2006
Soils and shallow groundwater at the former dry cleaning site were contaminated with perchloroethylene (PCE), a solvent commonly used in the dry cleaning ... - U.S. EPA.gov (press release),
Forex - US dollar firmer in Sydney morning, support ahead of key ... Feb 26, 2006
...against the euro and yen, while support is expected ahead of a number of key US data releases including price consumption expenditure data (PCE) for January ... - Forbes
FOREX-Dollar stages broad-based fall as PMI flags Feb 28, 2006
The GDP report showed inflation as measured by the personal consumption expenditures index, or PCE, edged up more than initially expected to a 2.7 percent ... - Reuters.uk,
PMI Supports the Euro Mar 1, 2006
Market players will also keep a sharp eye on the PCE deflator - the Fed's favorite gauge of inflation. If the ISM and Personal Spending ... - AME Info,
Capping private wells won't be put to a vote Mar 3, 2006
Some residents maintain that the amounts of tetrachloroethylene (also known as perchloroethylene or PCE) and trichloroethylene (TCE) found in some wells in ... - NorthJersey.com,
Core Inflation Eases Wall St.'s Worries, But Won't Stop Fed Feb 22, 2006
The core PCE deflator rose 1.9% in December vs. a year earlier. If the core PCE starts accelerating, "that would absolutely cement ... - Investor's Business Daily (subscription)
Pacific Asia China Energy Inc. Appoints Advisory Board Members Feb 21, 2006
...("PACE") (TSX VENTURE:PCE) is pleased to announce the appointment of Michael Halvorson and James Douglas Brown to the Company's recently formed Advisory Board. ... - Business Wire (press release),
Other information
Indication
For the conversion to sinus rhythm of paroxysmal supraventricular tachycardia (PSVT), including that associated with accessory bypass tracts (Wolff-Parkinson-White Syndrome)
Pharmacology
Adenosine is an endogenous nucleoside occurring in all cells of the body and is not chemically related to other antiarrhythmic drugs. Adenosine is indicated for the conversion to sinus rhythm of paroxysmal supraventricular tachycardia (PSVT), including that associated with accessory bypass tracts (Wolff-Parkinson-White Syndrome). Adenosine is antagonized competitively by methylxanthines such as caffeine and theophylline, and potentiated by blockers of nucleoside transport such as dipyridamole. Adenosine is not blocked by atropine.
Mechanism Of Action
Adenosine slows conduction time through the A-V node, can interrupt the reentry pathways through the A-V node, and can restore normal sinus rhythm in patients with paroxysmal supraventricular tachycardia (PSVT), including PSVT associated with Wolff-Parkinson-White Syndrome.
Drug Category
Vasodilator Agents; Antiarrhythmic Agents; Analgesics; Cardiac drugs; ATC:C01EB10
Brand Names/Synonyms
2'-Deoxyadenosine; Adenine Deoxy Nucleoside; Adenine Deoxyribonucleoside; Adenine Deoxyribose; Adenine Nucleoside; Adenine Riboside; Adenocard; Adenocor; Adenoscan; Adenosin; Adenosine; Adenosine 99%; Adenosine for Biochemistry; Adenosine, Free Base; Adensoine; Adenyldeoxyriboside; Boniton; CCRIS 1782; Da; Deoxyadenosine; Desoxyadenosine; Myocol; Nucleocardyl; Sandesin; Usaf Cb-10
Dosage Forms
LIQUID
Absorption
Not Available
Interactions
Interactions for Adenosine:
Intravenous Adenocard (adenosine) has been effectively administered in the presence of other cardioactive drugs,
such as quinidine, beta-adrenergic blocking agents, calcium channel blocking agents, and angiotensin converting
enzyme inhibitors, without any change in the adverse reaction profile. Digoxin and verapamil use may be rarely
associated with ventricular fibrillation when combined with Adenocard. Because of the potential for additive or
synergistic depressant effects on the SA and AV nodes, however, Adenocard should be used with caution in the presence
of these agents. The use of Adenocard in patients receiving digitalis may be rarely associated with ventricular
fibrillation.
The effects of adenosine are antagonized by methylxanthines such as caffeine and theophylline. In the presence of
these methylxanthines, larger doses of adenosine may be required or adenosine may not be effective. Adenosine effects
are potentiated by dipyridamole. Thus, smaller doses of adenosine may be effective in the presence of dipyridamole.
Carbamazepine has been reported to increase the degree of heart block produced by other agents. As the primary effect
of adenosine is to decrease conduction through the A-V node, higher degrees of heart block may be produced in the
presence of carbamazepine.
Chemical IUPAC Name
2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Chemical Formula
C10H13N5O4
Half Life
<10 secs
Drug Type
Approved Drug
# Accession No
APRD00132
CAS Registry Number
58-61-7