ANTINEOPLASTIC AGENTS


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AlemtuzumabFor treatment of B-cell chronic lymphocytic leukemia
AlitretinoinFor topical treatment of cutaneous lesions in patients with AIDS- related Kaposi sarcomaia.
AltretamineFor use as a single agent in the palliative treatment of patients with persistent or recurrent ovarian cancer following first-line therapy with a cisplatin and/or alkylating agent-based combination
AmsacrineFor treatment of acute myeloid leukaemia.
Arsenic TrioxideFor induction of remission and consolidation in patients with acute promyelocytic leukemia (APL), and whose APL is characterized by the presence of the t(15; 17) translocation or PML/RAR-alpha gene expression
AsparaginaseFor treatment of acute lympocytic leukemia and non-Hodgkins lymphoma
BevacizumabFor treatment of metastatic colorectal cancer
BexaroteneFor the treatment of cutaneous manifestations of cutaneous T-cell lymphoma in patients who are refractory to at least one prior systemic therapy
BleomycinFor palliative treatment in the management of the following neoplasms; Malignant neoplasm (trachea, bronchus, lung); Squamous cell carcinoma; Lymphomas
BusulfanFor use in combination with cyclophosphamide as a conditioning regimen prior to allogeneic hematopoietic progenitor cell transplantation for chronic myelogenous leukemia.
CapecitabineFor the treatment of patients with metastatic breast cancer resistant to both
CarboplatinFor the initial treatment of advanced ovarian carcinoma in established combination with other approved chemotherapeutic agents. One established combination regimen consists of PARAPLATIN and cyclophosphamide.
CarmustineFor the treatment of brain tumors, multiple myeloma, Hodgkin's disease and Non-Hodgkin's lymphomas.
CelecoxibFor relief and management of osteoarthritis (OA), rheumatoid arthritis (RA), ankylosing spondylitis, acute pain, primary dysmenorrhea and oral adjunct to usual care for patients with familial adenomatous polyposis
CetuximabFor treatment of metastatic colorectal cancer
ChlorambucilFor treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease
CisplatinFor the management of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.
CladribineFor the treatment of active Hairy Cell Leukemia as defined by clinically
CyclophosphamideFor management of malignant lymphomas, multiple myeloma, leukemias, mycosis fungoides (advanced disease), neuroblastoma (disseminated disease), adenocarcinoma of the ovary, retinoblastoma and carcinoma of the breast
CytarabineFor the treatment of acute non-lymphocytic leukemia, acute lymphocytic leukemia and blast phase of chronic myelocytic leukemia.
DacarbazineFor the treatment of metastatic malignant melanoma. in addition, DTIC-Dome is also indicated for Hodgkin's disease as a secondary-line therapy when used in combination with other effective agents
DactinomycinFor the treatment of Wilms' tumor, childhood rhabdomyosarcoma, Ewing's sarcoma and metastatic, nonseminomatous testicular cancer as part of a combination chemotherapy and/or multi-modality treatment regimen
DaunorubicinFor remission induction in acute nonlymphocytic leukemia (myelogenous, monocytic, erythroid) of adults and for remission induction in acute lymphocytic leukemia of children and adults
Denileukin diftitoxFor treatment of cutaneous T-cell lymphoma
DoxorubicinFor the Treatment of Koposi's sarcome connected to AIDS
EpirubicinFor use as a component of adjuvant therapy in patients with evidence of axillary node tumor involvement following resection of primary breast cancer
EstramustineFor the palliative treatment of patients with metastatic and/or progressive carcinoma of the prostate
EtoposideFor management of refractory testicular tumors and small cell lung carcinoma.
FludarabineFor the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to or whose disease has progressed during treatment with at least one standard alkylating-agent containing regimen
FluorouracilFor the topical treatment of multiple actinic or solar keratoses. in the 5% strength it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. Fluorouracil injection is indicated in the palliative management of some types of cancer, including colon, rectum, breast, stomach and pancrease.
GemcitabineFor the first-line treatment of patients with metastatic breast cancer , locally
Gemtuzumab ozogamicinFor treatment of acute myeloid leukemia
HydroxyureaFor management of melanoma, resistant chronic myelocytic leukemia, and recurrent, metastatic, or inoperable carcinoma of the ovary and Sickle-cell anemia
IdarubicinFor the treatment of acute myeloid leukemia (AML) in adults. This includes French-American-British (FAB) classifications M1 through M7.
IfosfamideFor third line chemotherapy of germ cell testicular cancer. It should ordinarily be used in combination with a prophylactic agent for hemorrhagic cystitis, such as mesna
IrinotecanFor the treatment of metastatic colorectal cancer (first-line therapy when administered with 5-fluorouracil and leucovorin)
LomustineFor use as a single agent in addition to other treatment modalities to treat
MarimastatFor the treatment of various cancers
MechlorethamineFor the palliative treatment of Hodgkinâ??s disease (Stages III and IV),
MelphalanUsed to treat cancer of the ovaries and a certain type of cancer in the bone marrow
MethotrexateFor the treatment of gestational choriocarcinoma, chorioadenoma destruens and hydatidiform mole; Severe psoriasis; Severe, active, classical or definite rheumatoid arthritis;
MitomycinFor treatment of malignant neoplasm of lip, oral cavity, pharynx, digestive
MitotaneFor treatment of inoperable adrenocortical tumours; Cushing's syndrome
MitoxantroneFor the treatment of secondary (chronic) progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis
OxaliplatinFor the treatment of malignant neoplasm of colon, rectum, and ovary
PaclitaxelFor the treatment of breast and ovarian cancer
PegaspargaseFor treatment of acute lymphoblastic leukemia
PemetrexedFor the treatment of malignant pleural mesothelioma and locally advanced or metastatic non-small cell lung cancer (NSCLC) after prior chemotherapy
PentostatinFor the treatment of hairy cell leukaemia refractory to alpha interferon
PipobromanFor the treatment of polycythaemia vera and refractory chronic myeloid leukaemia.
PorfimerIndicated in the treatment of esophageal cancer.
ProcarbazineFor use with other anticancer drugs for the treatment of stage III and stage IV Hodgkin's disease.
RaltitrexedFor the treatment of malignant neoplasm of colon and rectum
Rituximab For treatment of B-cell non-Hodgkins lymphoma (CD20 positive)
StreptozocinFor the treatment of malignant neoplasms of pancreas (metastatic islet cell
TemozolomideFor the treatment of adult patients diagnosed with anaplastic astrocytoma who have relapsed following chemotherapy
TeniposideTreatment of refractory acute lymphoblastic leukaemia
ThioguanineFor treatment of acute nonlymphocytic leukaemia
TopotecanFor the treatment of metastatic carcinoma of the ovary and small cell lung cancer following the failure of first-line chemotherapy.
TrastuzumabFor treatment of HER2-positive metatsatic breast cancer
TretinoinFor the the induction of remission in patients with acute promyelocytic leukemia (APL), French-American-British (FAB) classification M3 (including the M3 variant); For the topical treatment of acne vulgaris, flat warts and other skin conditions (psoriasis, ichthyosis congenita, icthyosis vulgaris, lamellar icthyosis, keratosis palmaris et plantaris, epidermolytic hyperkeratosis, senile comedones, senile keratosis, keratosis follicularis (Darier's disease), and basal cell carcinomas.); For palliative therapy to improve fine wrinkling, mottled hyperpigmentation, roughness associated with photodamage.
ValrubicinBladder cancer
VinblastineFor treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
VincristineFor treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, acute panmyelosis
VindesineFor the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia and acute panmyelosis
VinorelbineFor the treatment of non-small-cell lung carcinoma

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